Results 61 to 70 of about 1,210,569 (293)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Z-Scheme Heterojunction of SnS2/Bi2WO6 for Photoreduction of CO2 to 100% Alcohol Products by Promoting the Separation of Photogenerated Charges

open access: yesNanomaterials, 2022
Using sunlight to convert CO2 into solar fuel is an ideal solution to both global warming and the energy crisis. The construction of direct Z-scheme heterojunctions is an effective method to overcome the shortcomings of single-component or conventional ...
Yong Xu   +5 more
doaj   +1 more source

Charge expulsion, charge inhomogeneity and phase separation in dynamic Hubbard models

open access: yes, 2013
Dynamic Hubbard models are extensions of the conventional Hubbard model that take into account the fact that atomic orbitals expand upon double occupancy. It is shown here that systems described by dynamic Hubbard models have a tendency to expel negative
Hirsch, J. E.
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Electrostatic Field Formed by Charge Separation in Antiparallel Magnetic Reconnection

open access: yesThe Astrophysical Journal
The Hall effect resulting from the decoupled motions between ions and electrons is a critical factor in modeling collisionless magnetic reconnection. It leads to the production of charge separation in the reconnection plane, generating the electrostatic ...
Shihang Hu   +5 more
doaj   +1 more source

Spectral functions in a magnetic field as a probe of spin-charge separation in a Luttinger liquid

open access: yes, 2002
We show that the single-particle spectral functions in a magnetic field can be used to probe spin-charge separation of a Luttinger liquid. Away from the Fermi momentum, the magnetic field splits both the spinon peak and holon peak; here the spin-charge ...
Rabello, Silvio, Si, Qimiao
core   +1 more source

Charge renormalization and phase separation in colloidal suspensions [PDF]

open access: yes, 2000
We explore the effects of counterion condensation on fluid-fluid phase separation in charged colloidal suspensions. It is found that formation of double layers around the colloidal particles stabilizes suspensions against phase separation.
A Diehl   +9 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

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