Results 61 to 70 of about 374,258 (265)

Assessing intra- and inter-molecular charge transfer excitations in non-fullerene acceptors using electroabsorption spectroscopy

Nature Communications
Organic photovoltaic cells using Y6 non-fullerene acceptors have recently achieved high efficiency, and it was suggested to be attributed to the charge-transfer (CT) nature of the excitations in Y6 aggregates.
Sudhi Mahadevan, Taili Liu, Saied Md Pratik, Yuhao Li, Hang Yuen Ho, Shanchao Ouyang, Xinhui Lu, Hin-Lap Yip, Philip C. Y. Chow, Jean-Luc Brédas, Veaceslav Coropceanu, Shu Kong So, Sai-Wing Tsang   +12 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Charge transfer-tuned magnetism in Nd-substituted Gd5Si4

AIP Advances, 2018
We report a charge-transfer mechanism in tuning of magnetism of Nd-substituted Gd5-xNdxSi4 (x=1 and 2.5) compounds. The X-ray absorption near edge structure measurements demonstrated that Nd substitutions for Gd induce charge transfer of 5d electrons ...
R. H. Kou, J. Gao, Y. Ren, B. Sanyal, S. Bhandary, S. M. Heald, B. Fisher, C.-J. Sun   +7 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Recent advances in high charge density triboelectric nanogenerators

International Journal of Extreme Manufacturing
Triboelectric materials with high charge density are the building-block for the commercial application of triboelectric nanogenerators (TENGs).
Xin Cui, Jiaheng Nie, Yan Zhang
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Charge transfer complexes: a review survey

Results in Chemistry
Charge transfer complexes (CTCs) are formed when an electron donor interacts with an electron acceptor. A new compound (CTC) is generated through the formation of hydrogen bonds or charge transfer interactions.
Vahideh Hadigheh Rezvan
doaj   +1 more source

Charge Transfer between a Single Polymer Particle and Metal Plate by Impact [Translated]†

KONA Powder and Particle Journal, 2014
This paper describes an experimental investigation of the charge acquired by a single particle when striking a metal plate. The particle was projected from a pneumatic gun onto the metal plate.
Tatsushi Matsuyama, Hideo Yamamoto
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source