Results 61 to 70 of about 3,428,052 (302)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Limiting factors for charge generation in low-offset fullerene-based organic solar cells

Nature Communications
Free charge generation after photoexcitation of donor or acceptor molecules in organic solar cells generally proceeds via (1) formation of charge transfer states and (2) their dissociation into charge separated states.
Anna Jungbluth, Eunkyung Cho, Alberto Privitera, Kaila M. Yallum, Pascal Kaienburg, Andreas E. Lauritzen, Thomas Derrien, Sameer V. Kesava, Irfan Habib, Saied Md Pratik, Natalie Banerji, Jean-Luc Brédas, Veaceslav Coropceanu, Moritz Riede   +13 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Ground-state charge transfer in single-molecule junctions covalent organic frameworks for boosting photocatalytic hydrogen evolution

Nature Communications
Ground-state charge transfer plays a vital role in improving the photocatalytic performance of D-A type covalent organic frameworks. However, limited studies have explored the modulation of photocatalytic performance in COFs-based photocatalysts through ...
Rongchen Shen, Can Huang, Lei Hao, Guijie Liang, Peng Zhang, Qiang Yue, Xin Li   +6 more
doaj   +1 more source

Theoretical study on the conformation-dependent charge transfer of the excited state of dopamine

Heliyon
Clarifying the relationship between conformation and charge transfer is crucial for understanding the functional mechanisms of molecules in organisms. Theoretical calculations of dopamine, N,N-dimethyldopamine, and N,N-dihydroxydopamine were related to ...
Huan An, Asiya, Gulmire Yaermaimaiti, Bumaliya Abulimiti, Mei Xiang, Xiaoning Wang   +5 more
doaj   +1 more source

Programming/erasing efficiency of charge transfer photomemory [PDF]

APL Electronic Devices
Optically controlled non-volatile memory devices represent a promising paradigm for next-generation data storage, offering advantages such as high-speed, non-contact operation, and robust immunity to electromagnetic interference.
Heng-Shou Hsu, I-Ming Tseng, Wen-Luh Yang, I-Nan Chang   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Efficient Charge Generation Via Hole Transfer in Dilute Organic Donor-Fullerene Blends [PDF]

, 2019
Efficient organic photovoltaics (OPVs) require broadband charge photogeneration with near-unity quantum yield. This can only be achieved by exploiting all pathways that generate charge.
Alexander, Schubert, Jennifer P., Ogilvie, Yin, Song, Eitan, Geva, Xiao, Liu, Srijana, Bhandari, Stephen R., Forrest, Barry D., Dunietz   +7 more
core   +1 more source

Charge transfer and transport in DNA [PDF]

Proceedings of the National Academy of Sciences, 1998
We explore charge migration in DNA, advancing two distinct mechanisms of charge separation in a donor (d)–bridge ({B j })–acceptor (a) system, where {B j } = B 1 ,B 2 ...
J, Jortner, M, Bixon, T, Langenbacher, M E, Michel-Beyerle   +3 more
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source