Results 71 to 80 of about 702,376 (277)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

The role of pickup truck electrification in the decarbonization of light-duty vehicles

open access: yesEnvironmental Research Letters, 2022
Electrification can reduce the greenhouse gas (GHG) emissions of light-duty vehicles. Previous studies have focused on comparing battery electric vehicle (BEV) sedans to their conventional internal combustion engine vehicle (ICEV) or hybrid electric ...
Maxwell Woody   +6 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The Development of a Test Stand for Electric Fuel-Cell Turbocharger Integrity Testing—Part 2: Results

open access: yesEngineering Proceedings
This paper presents the results of a testbench regarding the effects of liquid water content in the turbine stage of a fuel-cell charging system. The testbench simulates the exhaust conditions of a PEM fuel cell to evaluate erosion potential in a single ...
Georgios Karakasis   +3 more
doaj   +1 more source

High Density Static Charges Governed Surface Activation for Long-Range Motion and Subsequent Growth of Au Nanocrystals

open access: yesNanomaterials, 2019
How a heavily charged metal nanocrystal, and further a dual-nanocrystals system behavior with continuous electron charging? This refers to the electric dynamics in charged particles as well as the crystal growth for real metal particles, but it is still ...
Guoxin Chen   +7 more
doaj   +1 more source

Charging of DMSP/F6 spacecraft in aurora on 10 January 1983 [PDF]

open access: yes, 1985
Spacecraft charging has been widely observed in geosynchronous orbit on the ATS-5 and ATS-6 pair and on the SCATHA spacecraft. An adequate theory for explaining the observations exist. Neither the data or theory can be exported to low polar orbit and its
Besse, A. L., Hardy, D. A., Rubin, A. G.
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Charged nanorods at heterogeneously charged surfaces [PDF]

open access: yesThe Journal of Chemical Physics, 2018
We study the spatial and orientational distribution of charged nanorods (rodlike counterions) as well as the effective interaction mediated by them between two plane-parallel surfaces that carry fixed (quenched) heterogeneous charge distributions. The nanorods are assumed to have an internal charge distribution, specified by a multivalent monopolar ...
Ali Naji   +3 more
openaire   +2 more sources

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