Results 51 to 60 of about 25,584 (170)

Collaborative optimization and regulation of the passenger cabin thermal environment by integrating machine learning modelling and the KMIGA control strategy

open access: yesEngineering Applications of Computational Fluid Mechanics
Computational Fluid Dynamics (CFD) serves as the mainstream method for developing thermal comfort in passenger cabins. However, its lengthy computational cycles and low simulation efficiency pose significant challenges in coupling with thermal management
Yingchao Zhang   +5 more
doaj   +1 more source

Polymer Concepts in Cellular Function

open access: yes
Advanced Science, EarlyView.
Miao Yu   +7 more
wiley   +1 more source

Retrospective Grid Cells in the Medial Entorhinal Cortex Encode Past Paths During Spatial Navigation

open access: yesAdvanced Science, EarlyView.
Retrospective grid cells are identified in the medial entorhinal cortex, with spatial firing patterns that become most grid‐like when activity is projected onto recently traversed locations. Their coding loses spatial precision in darkness and is disrupted during assisted movement, indicating that entorhinal representations incorporate recent path ...
Ruojin Liu   +10 more
wiley   +1 more source

Complete Pathway Refactoring and Combinatorial Biosynthesis of Anthracyclines for Modulation of Histone Eviction and DNA Damage Bioactivities

open access: yesAngewandte Chemie, EarlyView.
A synthetic biology platform was established for the complete refactoring of complex anthracycline biosynthetic pathways in Streptomyces coelicolor using standardized, chemically synthetic DNA parts. This modular construction enabled streamlined combinatorial biosynthesis, yielding novel analogs that decouple DNA damage from chromatin damage (histone ...
Rongbin Wang   +15 more
wiley   +2 more sources

Personalized Steering Feel Control Based on Driving Style Recognition and Closed-Loop Motion Regulation

open access: yesSensors
Against the backdrop of the continuous expansion of the automotive industry, consumer demand is undergoing a profound shift from quantity to quality. Conventional steering systems, due to their lack of dynamic adaptation to driver styles, struggle to ...
Hsin Guan   +8 more
doaj   +1 more source

Sonogenetic Control of Engineered Probiotics for the Treatment of MASH by Modulating the Gut‐Liver Axis

open access: yesAdvanced Science, EarlyView.
Researchers developed an engineered probiotic encapsulated in an inulin hydrogel, enabling ultrasound‐triggered intestinal delivery of IL‐22. In MASH model mice, this system remodeled gut microbiota, strengthened the intestinal barrier and reduced portal LPS and hepatic IL‐6.
Chunya Ji   +11 more
wiley   +1 more source

Comparative Analysis of Adaptation Behaviors of Different Types of Drivers to Steer-by-Wire Systems

open access: yesSensors
As one of the advanced automotive chassis technologies, the steer-by-wire system offers a high level of precision, responsiveness, and controllability in the driving experience.
Chen Chen   +3 more
doaj   +1 more source

Semi‐Artificial Photosynthesis Enables Light‐Driven Biomanufacturing in Non‐Photosynthetic Bacteria

open access: yesAdvanced Science, EarlyView.
A non‐invasive strategy exploits endogenous H2S metabolism in B. subtilis to drive in situ CdS biomineralization, enabling tight bio‐abiotic contact without genetic modification. Light harvested by the biomineralized nanoparticles powers NADPH regeneration, elevating 2’‐fucosyllactose and surfactin titres two‐ to three‐fold.
Jie Zheng   +8 more
wiley   +1 more source

Accelerating Biosensor Discovery: A Computationally‐Driven Pipeline for Microplastics Monitoring

open access: yesAdvanced Intelligent Discovery, EarlyView.
A computationally guided pipeline unites molecular simulation, synthetic biology, electrochemical engineering, and machine learning to accelerate biosensor discovery. A Bacillus anthracis carbohydrate‐binding module is used to develop a high‐performance micro‐ and nanoplastics sensor with greatly reduced error and variability.
Gabriel X. Pereira   +13 more
wiley   +1 more source

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