ABSTRACT This study addresses the need to understand human engagement with empathic Generative Artificial Intelligence (GenAI) digital companions (DC), as these systems increasingly fulfil social and emotional roles in daily life. Motivated by the rapid adoption of DC technologies and their potential to reshape human–AI relationships, the study applies
Aitor Ezker‐Galech +3 more
wiley +1 more source
Exploring Student Perceptions of Generative AI Therapists and Their Benefits and Challenges in Schools. [PDF]
Chan CKY, Tse S.
europepmc +1 more source
Feeling Vulnerable With My AI Companion: Examining Well‐Being in Human‐AI Relationships
ABSTRACT Individuals resort to human‐AI relationships to fulfill psychological, social, and empathetic needs. Nevertheless, dilemmas arise from these interdependent relationships which, although destined to enhance users' well‐being, can also be detrimental to them.
Liliane Abboud +2 more
wiley +1 more source
Efficacy, User Engagement, and Acceptability of Cognitive Behavioral Therapy-Oriented Psychological Chatbots for Adults With Depressive and/or Anxiety Symptoms: Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]
Gong B +6 more
europepmc +1 more source
ABSTRACT Despite the proliferation of artificial intelligence (AI) in marketing, consumers often exhibit algorithm discounting—a tendency to evaluate AI‐generated recommendations less favorably than those from humans. Focusing on consumption goals, this study investigates how anthropomorphic AI agents (virtual assistants vs.
Jiayue Huang +4 more
wiley +1 more source
A structured framework for effective and responsible generative artificial intelligence chatbot prompt engineering throughout the scientific process: a comprehensive guide for the health and medical researcher. [PDF]
Ng JY.
europepmc +1 more source
Quality and Readability of ChatGPT Performance on Parkinson's Disease
Abstract Background Chat Generative Pre‐trained Transformer (ChatGPT) is increasingly used for medical education and healthcare counseling. Objective To evaluate the reliability, quality, usefulness, and readability of ChatGPT‐4o responses to professional medical quizzes and patient frequently asked questions (FAQs) about Parkinson's disease (PD ...
Gabriele Riccio +4 more
wiley +1 more source
A Comparison of a Customized Peripheral Artery Disease (PAD)-Specific Generative AI Chatbot and General-Purpose AI Chatbots for PAD Patient Education. [PDF]
Cherif A +9 more
europepmc +1 more source
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley +1 more source

