Results 101 to 110 of about 10,320 (199)
Figure S6 from Synthetic Lethality Interaction Between Aurora Kinases and CHEK1 Inhibitors in Ovarian Cancer
, 2023 <p>Effect of Alisertib, LY2603618 and chemotherapies alone or in combination, in OVCAR3 and OVCAR8 growth as tumorspheres.</p>Alberto Ocaña, Atanasio Pandiella, Eva María Galán-Moya, Juan Llopis, Miguel Burgos, Juan Carlos Montero, Fernando Andrés-Pretel, Leticia Serrano-Oviedo, Verónica Corrales-Sánchez, Cristina Nieto-Jiménez, Ana Alcaraz-Sanabria +10 moreopenaire +1 more sourceMiR-126 negatively regulates PLK-4 to impact the development of hepatocellular carcinoma via ATR/CHEK1 pathway
Cell Death and Disease, 2018 Emerging evidence has shown that microRNA-126 (miR-126) is aberrantly downregulated and plays a vital role in carcinogenesis in various cancers, including HCC. However, the underlying biological mechanisms of miR-126 in HCC are still largely unknown.J. Bao, Yan Yu, Jianan Chen, Yuting He, Xiaolong Chen, Z. Ren, Chen Xue, Liwen Liu, Qiuyue Hu, Juan Li, G. Cui, R. Sun +11 moresemanticscholar +1 more sourceFigure S1 from Synthetic Lethality Interaction Between Aurora Kinases and CHEK1 Inhibitors in Ovarian Cancer
, 2023 <p>Dose-response curves in the human keratinocyte cell line, HACAT and Synergistic effect of Alisertib, LY2603618 and chemotherapies.</p>Alberto Ocaña, Atanasio Pandiella, Eva María Galán-Moya, Juan Llopis, Miguel Burgos, Juan Carlos Montero, Fernando Andrés-Pretel, Leticia Serrano-Oviedo, Verónica Corrales-Sánchez, Cristina Nieto-Jiménez, Ana Alcaraz-Sanabria +10 moreopenaire +1 more sourceLegends to Supplementary Material from Synthetic Lethality Interaction Between Aurora Kinases and CHEK1 Inhibitors in Ovarian Cancer
, 2023 Ana Alcaráz-Sanabria, Cristina Nieto‐Jiménez, Verónica Corrales‐Sánchez, Leticia Serrano‐Oviedo, Fernando Andrés‐Pretel, Juan Carlos Montero, Miguel Burgos, Juan Llopis, Eva María Galán‐Moya, Atanasio Pandiella, Alberto Ocaña +10 moreopenalex +1 more sourceOverexpression of Opa interacting protein�5 increases the progression of liver cancer via BMPR2/JUN/CHEK1/RAC1 dysregulation
Oncology Reports, 2019 Opa interacting protein 5 (OIP5) overexpression is associated with human carcinoma. However, its biological function, underlying mechanism and clinical significance in liver cancer remain unknown. In the present study, the effects of OIP5 expression on liver cancer, and the mechanisms regulating these effects, were investigated.Li, Yuwen, Xiao, Fei, Li, Wenting, Hu, Pingping, Xu, Ruirui, Li, Jun, Li, Guimei, Zhu, Chuanlong +7 moreopenaire +3 more sourcesCausal Effects of Oxidative Stress on Diabetes Mellitus and Microvascular Complications: Insights Integrating Genome-Wide Mendelian Randomization, DNA Methylation, and Proteome
AntioxidantsBackground: Oxidative stress (OS) is involved in the development of diabetes, but the genetic mechanisms are not completely understood. We integrated multi-omics data in order to explore the genetic relations between OS-related genes, diabetes mellitus ...Kang Liu, Zitong Chen, Lishan Liu, Ting Li, Changying Xing, Feng Han, Huijuan Mao +6 moredoaj +1 more sourceData from Thymoquinone Triggers Inactivation of the Stress Response Pathway Sensor <i>CHEK1</i> and Contributes to Apoptosis in Colorectal Cancer Cells
, 2023 Hala Gali‐Muhtasib, Doerthe Kuester, Christian Mawrin, Khuloud Bajbouj, Antje Diestel, Matthias Ocker, Caroline Habold, Charlotte Foltzer‐Jourdainne, Peter Schoenfeld, Brigitte Peters, Mona Diab‐Assaf, Ulf Pommrich, Wafica Itani, H. Lippert, Albert Roessner, Regine Schneider‐Stock +15 moreopenalex +1 more sourceData from Endogenous Replication Stress Marks Melanomas Sensitive to CHEK1 Inhibitors <i>In Vivo</i>
, 2023 Zay Yar Oo, Alexander J. Stevenson, Martina Proctor, Sheena M. Daignault, Sebastian Walpole, Catherine Lanagan, James Chen, Dubravka Škalamera, Loredana Spoerri, Stephen A. Ainger, Richard A. Sturm, Nikolas K. Haass, Brian Gabrielli +12 moreopenalex +1 more sourceFigure S1, Figure S2, Figure S3, Figure S4, Figure S5, Figure S6, Figure S7, Table S1 from Endogenous Replication Stress Marks Melanomas Sensitive to CHEK1 Inhibitors <i>In Vivo</i> [PDF]
, 2023 Zay Yar Oo, Alexander J. Stevenson, Martina Proctor, Sheena M. Daignault, Sebastian Walpole, Catherine Lanagan, James Chen, Dubravka Škalamera, Loredana Spoerri, Stephen A. Ainger, Richard A. Sturm, Nikolas K. Haass, Brian Gabrielli +12 moreopenalex +1 more sourceFigure S4 from Synthetic Lethality Interaction Between Aurora Kinases and CHEK1 Inhibitors in Ovarian Cancer
, 2023 Ana Alcaráz-Sanabria, Cristina Nieto‐Jiménez, Verónica Corrales‐Sánchez, Leticia Serrano‐Oviedo, Fernando Andrés‐Pretel, Juan Carlos Montero, Miguel Burgos, Juan Llopis, Eva María Galán‐Moya, Atanasio Pandiella, Alberto Ocaña +10 moreopenalex +1 more source
