Safe and precise bioorthogonal therapy of tumors was achieved by an ultrasound‐responsive heterostructured nanoreactor with on‐demand catalytic activity. Under piezoelectric catalysis, the system undergoes reversible Pd2+/Pd0 redox cycling, concurrently enabling spatiotemporally controlled prodrug activation and self‐terminating catalytic dose ...
Daqing Xia +9 more
wiley +1 more source
Olefin Metathesis Catalyzed by a Latent Ruthenathiete Complex. [PDF]
Pabarue AB +4 more
europepmc +1 more source
Radioresistance arises partly from tumor cells evading cuproptosis via unknown defenses. This study reveals that the PRMT5‐VPS34 axis acts as a radiation‐activated anticuproptotic mechanism: PRMT5 methylates VPS34 at Arg174, recruiting USP10 to remove K48‐linked ubiquitination and prevent degradation.
Wei Chen +17 more
wiley +1 more source
Structure elucidation and evaluation of the antimicrobial and antitumor activities of 5-methylthiazole-based Schiff base and its metal chelates. [PDF]
Wahdan KM +4 more
europepmc +1 more source
A NIR‐II light‐activatable thermoelectric nanoreactor converts surface‐bound Cu2+ into bioactive Cu+ via directed electron flow. This spatiotemporally controlled reduction triggers potent cuproptosis and immunogenic cell death, eradicating primary tumors and, together with aPD‐1 therapy, suppressing metastases while establishing durable immune memory ...
Boyu Yuan +10 more
wiley +1 more source
Tensile strain regulation via grain boundary buffering for flexible perovskite solar cells. [PDF]
Xu Z +9 more
europepmc +1 more source
A novel PR strategy was proposed to improve CBD‐derived Sb2S3 film quality. It synergistically optimized the CBO of CdS/Sb2S3 interface and the back‐contact barrier, while the VS2 donor defect was converted into SSb2 acceptor defect with lower concentration.
Yeyang Lin +8 more
wiley +1 more source
Coordination versatility and enhanced bioactivity of Co<sup>2+</sup>, Cu<sup>2+</sup> and Cd<sup>2+</sup> complexes derived from pyridyl Schiff base: structural, electronic and electrochemical insights. [PDF]
Elshewemy AK +6 more
europepmc +1 more source
Calcium‐Mechanochemistry Enabled Ketone Synthesis From Organic Iodides and Carboxylic Acids
Mechanochemically generated organocalcium species display unusual chemoselectivity toward carboxylates, enabling direct ketone synthesis without overaddition. Ball milling activates commercial calcium metal under ambient, solvent‐minimized conditions, providing a broad substrate scope, high functional‐group tolerance, and a practical one‐step ...
Mengyao Pei +9 more
wiley +1 more source
Zinc Chelates from Low-Molecular-Weight Donkey-Hide Gelatin Peptides: Preparation, Characterization, and Evaluation of In Vitro Antioxidant Activity. [PDF]
Han W +7 more
europepmc +1 more source

