Results 251 to 260 of about 29,819 (311)
Some of the next articles are maybe not open access.
To chelate or not to chelate in MDS: That is the question!
Blood Reviews, 2018Myelodysplastic syndromes (MDS) are a heterogeneous group of hemopathies that exhibit physical manifestations with clinical consequences of bone marrow failure and inherent risk of progression to acute myeloid leukemia. Iron overload (IO) is common in MDS due to chronic transfusion support and disease-related alterations in iron metabolism. IO has been
Amer M, Zeidan, Elizabeth A, Griffiths
openaire +2 more sources
Blood Reviews, 1990
Adequate iron chelation in thalassaemia has resulted in a striking improvement in survival, with a reduction of cardiac mortality at age 15 years from 14-3%, and a predicted survival at age 36 years of 85%. Long term desferrioxamine (DF) therapy in thalassaemic children should be started between 2-4 years of age.
C, Hershko, A, Pinson, G, Link
openaire +3 more sources
Adequate iron chelation in thalassaemia has resulted in a striking improvement in survival, with a reduction of cardiac mortality at age 15 years from 14-3%, and a predicted survival at age 36 years of 85%. Long term desferrioxamine (DF) therapy in thalassaemic children should be started between 2-4 years of age.
C, Hershko, A, Pinson, G, Link
openaire +3 more sources
Chemotherapy, 2000
The antibacterial activity of metal ions, metal chelates, and molecules with chelating ability for polyvalent cations have been evaluated. The chelator N,N′-ethylenebis[2-(2-hydroxyphenyl)-glycine] (EHPG) exerted moderate-to-good activity against isolates of pathogenic bacteria and fungi. Other chelating agents such as ethylenediamine-tetraacetic acid (
Tom Bergan +5 more
openaire +2 more sources
The antibacterial activity of metal ions, metal chelates, and molecules with chelating ability for polyvalent cations have been evaluated. The chelator N,N′-ethylenebis[2-(2-hydroxyphenyl)-glycine] (EHPG) exerted moderate-to-good activity against isolates of pathogenic bacteria and fungi. Other chelating agents such as ethylenediamine-tetraacetic acid (
Tom Bergan +5 more
openaire +2 more sources
Annual Review of Medicine, 2009
Deferoxamine (DFO) was the standard of care for transfusional iron overload for >40 years, requiring subcutaneous infusion for 8–12 h/day, 5–7 days/week. Oral iron chelators are an important development, offering the potential to improve compliance and patients’ quality of life.
M.D. Cappellini, P. Pattoneri
openaire +2 more sources
Deferoxamine (DFO) was the standard of care for transfusional iron overload for >40 years, requiring subcutaneous infusion for 8–12 h/day, 5–7 days/week. Oral iron chelators are an important development, offering the potential to improve compliance and patients’ quality of life.
M.D. Cappellini, P. Pattoneri
openaire +2 more sources
Boron chelates and boron-metal chelates
Fresenius' Zeitschrift für analytische Chemie, 1983Seven chelates were synthesized from aliphatic diamines, salicylaldehyde and diphenylboric anhydride. Chelates with a B(C6H5)2 group could not be obtained with the α, ω-diamines used. The compounds were studied by elementary analysis and molecular spectroscopy (UV, IR, NMR: 1H, 13C). The solubilities of the compounds were determined in dichloromethane.
openaire +1 more source
Current Opinion in Hematology, 2014
This review provides an update on advances in the area of iron chelation therapy, including new indications and uses of currently available agents, and preliminary data on potential new agents in development.Two new oral agents, deferasirox and deferiprone, have become available in the last 8 years.
openaire +2 more sources
This review provides an update on advances in the area of iron chelation therapy, including new indications and uses of currently available agents, and preliminary data on potential new agents in development.Two new oral agents, deferasirox and deferiprone, have become available in the last 8 years.
openaire +2 more sources
Chelating Agents and Metal Chelates
Archives of Biochemistry and Biophysics, 1964openaire +2 more sources
Synthesis, characterization, DNA binding, and biological action of dimedone arylhydrazone chelates
Applied Organometallic Chemistry, 2022Mohamed El-Bindary, Ashraf El-Bindary
exaly