Results 151 to 160 of about 42,764 (248)

Strategies for inducing diabetes in laboratory animals: Advances from chemical, surgical, immunologic, dietary, and genetic approaches

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This review summarizes the principal experimental approaches used to induce diabetes in animal models. Strategies include chemical agents (streptozotocin, alloxan, dithizone, gold thioglucose), dietary interventions (high‐fat and high‐sugar diets), surgical methods (total or partial pancreatectomy), genetic models (db/db, ob/ob, Goto‐Kakizaki [GK ...
Milad Faraji   +2 more
wiley   +1 more source

Solution Synthesis of Actinide Chalcogenide and Oxychalcogenide Nanoparticles

open access: yesAngewandte Chemie, EarlyView.
We report the synthesis of UOS, UOSe, and US2 nanoparticles under colloidal conditions. The magnetic properties were measured of all three materials and compared to prior studies of UO2 nanoparticles. Nanoparticle phases were determined using powder diffraction, and size by transmission electron microscopy.
Cheyenne Orozco   +7 more
wiley   +2 more sources

Bifunctional Hexadentate Pyclen-Based Chelating Agent for Mild Radiofluorination in Aqueous Solution at Room Temperature with a Ga-18F Ternary Complex. [PDF]

open access: yesChemistry
Dioury F   +10 more
europepmc   +1 more source

Deferasirox, an Iron-Chelating Agent, Improves Testicular Morphometric and Sperm Functional Parameters in a Rat Model of Varicocele. [PDF]

open access: yesOxid Med Cell Longev, 2021
Rahmani M   +9 more
europepmc   +1 more source

Sappanwood extract modulates hepatic structure–function in hepatomegaly and hepcidin related iron regulatory pathways in a phenylhydrazine induced hemolytic anemia rat model relevant to thalassemia

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Phenylhydrazine (PHZ) induces hemolytic anemia characterized by increased erythrocyte destruction and ineffective erythropoiesis, leading to hepcidin suppression through disruption of the BMP/SMAD signaling pathway. Reduced hepcidin levels enhance intestinal iron absorption and hepatic iron accumulation, leading to hepatic iron overload.
Mohammad Indra Pratama   +5 more
wiley   +1 more source

Water, Alcohols, Amines, and Amides as Formal Hydrogen‐Atom‐Transfer Reagents Through Activation With Redox‐Active Lewis Acids

open access: yesAngewandte Chemie, EarlyView.
Protic molecules containing strong O─H or N─H bonds typically resist hydrogen‐atom abstraction because of the high reactivity of the resulting heteroatom‐centered radicals. However, association of the protic molecules with redox‐active Lewis acids can provide powerful hydrogen‐atom donors or proton‐coupled‐electron‐transfer reagents.
Petra Vojáčková, Armido Studer
wiley   +2 more sources

Antibacterial Synthetic Nanocelluloses Synergizing with a Metal-Chelating Agent. [PDF]

open access: yesACS Appl Bio Mater
Serizawa T   +8 more
europepmc   +1 more source

Borylcyclopropanes: Synthetic Strategies and Applications

open access: yesAngewandte Chemie, EarlyView.
Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley   +2 more sources

Efficacy of the iron-chelating agent, deferiprone, in patients with Parkinson's disease: A systematic review and meta-analysis. [PDF]

open access: yesCNS Neurosci Ther
Negida A   +9 more
europepmc   +1 more source

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