Results 161 to 170 of about 3,847,034 (280)

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

Advanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang, Xiangyao Wang, Yaxin Wu, Liping Liu, Gaoshaer Nuerlan, Ahsawle Ozathaley, Xiaorui Zhang, Jinping Wang, Bowen Yang, Jing Mao, Yan Liu, Shiqiang Gong   +11 more
wiley   +1 more source

Diagnosis of LVAD thrombus using a high-avidity fibrin-specific 99mTc probe [PDF]

, 2018
Akinobu Itoh, Anne H. Schmieder, Dmitry D. Beyder, Grace Cui, Gregory A. Ewald, Gregory M. Lanza, John S. Allen, Krishna S. Paranandi, Michael J. Scott, Michael Nassif, Samuel Achilefu, Walter J. Akers   +11 more
core   +2 more sources

In Situ Polymerized Composite Electrolytes for High‐Performance Solid‐State Lithium Batteries: A Review

Advanced Science, EarlyView.
This review systematically explores the recent advances in in situ polymerized composite polymer electrolytes (CPEs) for solid‐state lithium batteries. It covers the fundamentals of reaction mechanisms, monomer chemistry, and their impact on interfacial stability, ionic conductivity, and electrochemical performance.
Jialin Li, Yufen Yan, Xiaoju Wang, Yuhui Huang, Zhen Huang, Lingjie Zhang, Ningzhong Bao, Zijian Hong, Yongjun Wu, Dali Ji   +9 more
wiley   +1 more source

Decoding the Mechanism of Action of a Parasite TGFβ Antagonist Inspires the Creation of Cell‐Type‐Specific TGFβ Modulators

Advanced Science, EarlyView.
The mammalian TGFβ interacts with ubiquitously expressed TGFBR1 and TGFBR2, and current TGFβ‐targeting agents are non‐cell‐selective. The cooperative interaction of the modular parasite TGFβ antagonist with multiple host (co‐)receptors empowers the design of TGM chimeras and bispecific antibodies that activate or inhibit TGFβ signaling in a cell ...
Maarten van Dinther, Tristin Schwartze, Jiying Zhang, Kun Fan, Gerard van der Zon, Luke Power, Cynthia S. Hinck, Claire Ciancia, Ananya Mukundan, Roman Gonzalez‐Prieto, Peter van Veelen, Rick M. Maizels, Andrew P. Hinck, Peter ten Dijke   +13 more
wiley   +1 more source

Strategies Toward Accessing Enantioenriched (Hetero)Benzo‐Fused 5‐ and 6‐ Membered Rings via Intermolecular Carbometalation

Angewandte Chemie, EarlyView.
The use of transition‐metal catalysts and design of chiral ligands have allowed chemists to access highly functionalized benzofused 5‐ and 6‐ membered rings in high yield and enantioselectivity. A common strategy used relies on an intermolecular carbometalation across alkynes and olefins, usually followed by a subsequent intramolecular carbometalation.
Clara Jans, Armaan Grewal, Xavier Abel‐Snape, Mark Lautens   +3 more
wiley   +2 more sources

Enhancing Li‐S Battery Performance Through Low‐Concentration Electrolytes with Organic Se/Te Co‐Additives to Address Solubility and Kinetic Challenges

Advanced Science, EarlyView.
This work presents a low‐concentration electrolyte enabled by hybrid organic Se/Te additives (DPDSe/DPDTe) that restructures solvation, boosts polysulfide dissolution, and provides dual‐site synergistic catalysis, delivering high capacity and stable cycling in Li–S coin and pouch cells, supporting high‐energy, high‐power operation.
Ruihua Li, Haiwei Wu, Hairu Wei, Wenhao Jia, Frederik Bettels, Leon Schenk, Zhihua Lin, Hanbin Liu, Guodong Liu, Zhijian Li, Lin Zhang   +10 more
wiley   +1 more source

Trapping a Metastable Node in an Amorphous Metal–Organic Framework

Angewandte Chemie, EarlyView.
Frustrated assembly in an amorphous Fe‐BDC framework is shown to trap a distorted, metastable Fe3O node as the dominant local motif. X‐ray PDF analysis and DFT calculations reveal that rapid network percolation outpaces node relaxation, locking in a high‐energy puckered geometry.
Adam F. Sapnik, Emma H. Wolpert, Jens Edelvang‐Pejrup, Nanna L. Baun, Heloisa N. Bordallo, Kirsten M. Ø. Jensen   +5 more
wiley   +2 more sources

From Materials to Systems: Challenges and Solutions for Fast‐Charge/Discharge Na‐Ion Batteries

Advanced Energy Materials, EarlyView.
This review systematically analyzes the key characteristics limiting the fast‐charge/discharge capability of Na‐ion batteries (SIBs) from a multi‐scale perspective encompassing electrode materials, the electrode‐electrolyte interface, and the system. Furthermore, it presents practical solution strategies for the fundamental issues arising at each scale,
Bonyoung Ku, Sangbin Park, Sunha Hwang, Sunghyun Lim, Won‐Sub Yoon, Jongsoon Kim   +5 more
wiley   +1 more source

Recent Advances in Nano‐Microstructured Catalysts for Electrochemical Seawater Electrocatalysis

Advanced Energy Materials, EarlyView.
This review highlights advances in nano‐ and microstructured catalysts for electrochemical seawater conversion. It elucidates design principles, mechanistic understanding, and machine‐learning‐assisted discovery, and outlines key challenges and future opportunities toward efficient, selective, and durable seawater electrocatalysis.
Xiaodong Shao, Mengfang Liang, Xiaotong Han, Xu Yu, Huan Pang, Ho Seok Park   +5 more
wiley   +1 more source

Molecular Design and Interfacial Functions of Self‐Assembled Monolayers for Perovskite and Tandem Solar Cells

Advanced Energy Materials, EarlyView.
We identify two decisive levers for SAM interfaces: molecular design (carboxylic acid‐based, phosphonic acid, other anchoring chemistries, and polymeric SAMs) and mixing routes (co‐assembly, in situ assembly, pre‐ and post‐treatment). Coordinated tuning of headgroups and assembly pathways optimises energy alignment and film formation, suppresses ...
Jiaxu Zhang, Bochun Kang, Feng Yan
wiley   +1 more source