Results 181 to 190 of about 3,468,535 (384)

GSH as an A‐A Type Allosteric Activator of PKM2: Modulating Cancer Cell Homeostasis and Ferroptosis Susceptibility

open access: yesAdvanced Science, EarlyView.
Glutathione (GSH) defines oxidative balance, but can it directly tune central metabolism? The research reveals that GSH binds and potently activates pyruvate kniase M2 (PKM2), rewiring glycolysis and dictating ferroptosis sensitivity. Combining GSH depletion with PKM2 activation triggers mitochondrial damage and lipid peroxidation, profoundly ...
Tsan‐Jan Chen   +17 more
wiley   +1 more source

The Role of the Chelating Agent on the Structure and Anticorrosion Performances of an Organosilane—Zirconium Sol-Gel Coatings

open access: hybrid, 2018
Mary C. O’Sullivan   +6 more
openalex   +2 more sources

Oral acetylated whey peptides (AWP) as a potent antioxidant, anti-inflammatory, and chelating agent in iron-overloaded rats' spleen

open access: gold, 2023
Ahmed Y. Nassar   +7 more
openalex   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

open access: yesAdvanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li   +7 more
wiley   +1 more source

CATHODE RAY TUBE (CRT) LEAD GLASS: LEAD LEACHING STUDY AFTER A CHELATING AGENT TREATMENT

open access: diamond, 2015
Elena Bursi   +5 more
openalex   +1 more source

NADH‐Reductive Stress Induced by Dihydrolipoamide Dehydrogenase Activation Contributes to Cuproptosis

open access: yesAdvanced Science, EarlyView.
This study demonstrates a cuproptosis mechanism involving nicotinamide adenine dinucleotide (NADH)‐reductive stress in neural cells. Copper activates dihydrolipoamide dehydrogenase under mitochondrial pH, accumulating NADH. Copper also induces mitochondrial permeability transition pore opening, facilitating NADH translocation to the cytosol and ...
Si‐Yi Zhang   +3 more
wiley   +1 more source

A perspective Study on Lead Poisoning: Exposure, Effects and Treatment

open access: yesInternational Journal of Economic and Environment Geology, 2019
Current studies focus on various aspects of lead ‘s poisoning, its distribution and interaction routes, adverse effects on human body and treatment procedures. Lead metal has been involved in human exercise from the past 6000 years.
Mishal Chaudhari, Shabbir Hussain, Hajira Rehman, Tanzeela Gulab Shahzady
doaj  

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