Results 181 to 190 of about 49,786 (249)

Electron compensation‐gated nanomotor for immunomodulation and microenvironment remodeling in bacterial pneumonia therapy

open access: yesBMEMat, EarlyView.
A nanomotor featuring an “electronic lock” via electron compensation in an Au‐Ag alloy ensures therapeutic precision. Near‐infrared light acts as a key, unlocking on‐demand Ag+ release for synergistic bactericidal action and microenvironment remodeling to potently treat bacterial pneumonia. Abstract Bacterial pneumonia treatment is severely hampered by
Chenglong Xue   +4 more
wiley   +1 more source

High Entropy–Driven Performance Enhancement in Perovskite Oxides for Energy Conversion and Storage Systems

open access: yesCarbon Energy, EarlyView.
High‐entropy perovskite oxides enable tunable structures and properties through multi‐cation disorder and entropy stabilization. This review summarizes advances in synthesis, structural and defect engineering, and their applications in OER/ORR, CO2RR, and electrochemical energy storage, highlighting in situ characterization and modeling that clarify ...
Obeylaw Moyo   +8 more
wiley   +1 more source

Protective Effect of Phytic Acid in Cardiovascular Diseases: A Systematic Review

open access: yesChemFoodChem, EarlyView.
ABSTRACT Cardiovascular diseases (CVDs) are a cluster of ailments that impact the heart and blood vessels and are a primary public health problem of mortality on a global scale. Phytic acid, a dietary constituent frequently present in foods like seeds, has been linked to many pharmacological attributes, including anti‐cancer, antioxidant, anti ...
Marta M. S. de Freitas Almeida   +7 more
wiley   +1 more source

Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers

open access: yesChemistry – A European Journal, EarlyView.
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda   +5 more
wiley   +1 more source

Cationic Sulfonium‐Based Tripodal Ligand and Its Rh(I) Complexes

open access: yesChemistry – A European Journal, EarlyView.
We report a cationic EP3‐type tripodal ligand based on an aromatic sulfonium cation (E = S+) along with a series of its Rh(I) complexes. Structural, spectroscopic, electrochemical, and computational analyses of these complexes compared to isostructural analogs (E = Si− or P) reveal pronounced electron density depletion at Rh in the sulfonium congener ...
Nitsan Barel   +5 more
wiley   +1 more source

Homo‐/Heterodimeric Substrates Bias the Type and Multiplicity of Hydroxamic Acid Chelators Assembled by a NIS Synthetase DesD

open access: yesChemistry – A European Journal, EarlyView.
Chemoenzymatic reactions using the siderophore synthetase DesD from Salinispora tropica and hydroxamic acid substrates (native, non‐native) with different multiplicities (monomer, dimer) and components (homo‐/heterodimer) followed different reaction trajectories, which biased the architectures of the chelator major products and indicated DesD contains ...
Callum A. Rosser   +2 more
wiley   +1 more source

Cyclen Tetra‐Amide Ligands as a Privileged Class of Ligands for Studying Second‐Sphere Coordination Environments

open access: yesChemistry – A European Journal, EarlyView.
Cyclen tetra‐amide derivatives provide a privileged ligand platform for controlling second‐coordination sphere structure. Hydrogen‐bond networks in the second‐coordination sphere are leveraged to stabilize a EuII‐containing cyclen tetra‐amide derivative in physiologically relevant conditions by limiting the access of O2, establishing a design‐principle
Andrea L. Batchev   +5 more
wiley   +1 more source
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Chelating Agents

Chemotherapy, 2000
The antibacterial activity of metal ions, metal chelates, and molecules with chelating ability for polyvalent cations have been evaluated. The chelator N,N′-ethylenebis[2-(2-hydroxyphenyl)-glycine] (EHPG) exerted moderate-to-good activity against isolates of pathogenic bacteria and fungi. Other chelating agents such as ethylenediamine-tetraacetic acid (
Tom Bergan   +5 more
openaire   +4 more sources

Chelating Agents in Medicine

Journal of Toxicology: Clinical Toxicology, 1982
AbstractIn recent years there has been a growing awareness of the importance of trace metals in the environment, in their dichotomous role as essential nutritional factors on the one hand, and as toxic agents on the other. The apparent ambivalent nature of metal ions is shown as a continuum in a wide range dose-response curve. The response on the curve,
D R, Williams, B W, Halstead
openaire   +2 more sources

Therapeutic chelating agents

Journal of Chemical Education, 1976
The authors relay promising pharmceuticals to treat lead poisoning and other common heavy metal toxins.
M M, Jones, T H, Pratt
openaire   +2 more sources

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