Results 111 to 120 of about 70,599 (218)

Mercury-associated minimal change disease induced by whitening cream: a case report. [PDF]

Front Med (Lausanne)
Zhou WJ, Li XN, Zhang W, Yang YQ.
europepmc   +1 more source

Loss of LCN2 Function Ameliorates Glucocorticoid‐Induced Muscle Atrophy via Remodeling the Extracellular Matrix

Advanced Science, EarlyView.
Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi, Xiaojing Hao, Yi Yan, Fengyang Li, Yaru Zhang, Zixin Li, Wenjuan Xie, Jiayin Lu, Xiaomao Luo, Yanjun Dong, Haidong Wang, Juan Wang   +11 more
wiley   +1 more source

Liver iron concentration and renal dysfunction in β-thalassemia: a case series and exploratory clinical observations. [PDF]

Ann Hematol
Kabbara F, Charbel N, El Khoury S, Klim J, Ismail G, Ismail F, Fawaz H, Koussa S, Taher A.   +8 more
europepmc   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source

FPN1-8C>G Polymorphism as a potential genetic modifier of iron overload in transfusion-dependent β-Thalassemia major patients receiving HbF augmentation therapy. [PDF]

Pak J Med Sci
Wadood M, Siddiqi MYJ, Nazir I, Rizwan M.   +3 more
europepmc   +1 more source

Disease‐Stage Synchronized Nanozyme Therapy for Polymicrobial Sepsis through Adaptive Catalytic and Immune Reprogramming

Advanced Science, EarlyView.
A disease‐stage synchronized nanozyme platform is developed to treat polymicrobial sepsis by adapting its functions to changing infection environments. The system eliminates multidrug‐resistant bacteria during early infection while reducing inflammation and restoring immune balance during recovery, providing an integrated strategy for infection control
Anlai Zou, Xiaoxue Zhu, Runhan Zhu, Chengchu Xue, Qinyu Zhang, Mengke Li, Ting Yu, Yuzhen Gao, Zhi Ruan, Ying Fu, Yunlei Xianyu, Jun Zhang   +11 more
wiley   +1 more source

Effect of HFE Gene H63D and S65C Mutations on the Severity of Secondary Iron Overload in Children With β-Thalassemia Major. [PDF]

Cureus
Ali SK, Ali EW.
europepmc   +1 more source

Bidirectional Soft Catalysts for Improved Power Performance of Li‐S Batteries

Advanced Science, EarlyView.
A soft polymer‐metal catalyst is integrated into the binder to create a catalytically active microenvironment that accelerates bidirectional sulfur redox kinetics in lithium‐sulfur batteries. A model polyvinyl alcohol‐Cu catalyst enables high areal capacities at demanding current densities and stable cycling in pouch‐cell prototypes at 0.5 C, achieving
Maleesha M. Nishshanke, Petar Jovanovic, Swarit Dwivedi, Declan McNamara, Akshat Tanksale, Mahdokht Shaibani, Matthew Hill, Mainak Majumder   +7 more
wiley   +1 more source

Impact of renal iron overload on sickle cell nephropathy in a humanized mouse model. [PDF]

Am J Physiol Renal Physiol
Sako MO, Kane BJ, Booze M, Walker S, Patel M, Swamigari S, Nguyen H, Hyndman KA, Mitchell T, Bolisetty S, Kasztan M.   +10 more
europepmc   +1 more source

Low SLC8A1 in Colorectal Cancer Dictates Radiotherapy Resistance Through Calcium‐Dependent ANXA2+sEVs Driving M2 Polarization of TAMs

Advanced Science, EarlyView.
SLC8A1 deficiency in colorectal cancer cells increases intracellular calcium signaling, promoting the secretion of ANXA2‐enriched small extracellular vesicles. These vesicles reprogram tumor‐associated macrophages towards an M2 phenotype, which in turn fosters a tumor microenvironment conducive to radioresistance and is associated with poor patient ...
Yimin Fang, Jinghan Zhu, Qian Xiao, Qichun Wei, Xiujing He, Ping Li, Kai Jiang, Yue Liu, Yeting Hu, Weiwei Yu, Chuansheng Guo, Sheng Chen, Jian Zhao, Siqi Dai, Jingsun Wei, Hang Yang, Tongtong Bu, Kefeng Ding, Haiyan Chen   +18 more
wiley   +1 more source