Results 151 to 160 of about 4,382,200 (272)

The First Chemical Census of the Milky Way’s Nuclear Star Cluster

The Astrophysical Journal Letters
An important step in understanding the formation and evolution of the nuclear star cluster (NSC) is to investigate its chemistry and chemical evolution. Additionally, exploring the NSC’s relationship to the other structures in the Galactic center and the
Govind Nandakumar, Nils Ryde, Mathias Schultheis, R. Michael Rich, Paola di Matteo, Brian Thorsbro, Gregory Mace   +6 more
doaj   +1 more source

Chemical feature of Eu abundance in the Draco dwarf spheroidal galaxy [PDF]

, 2015
Takuji Tsujimoto, Miho N. Ishigaki, Toshikazu Shigeyama, Wako Aoki   +3 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Tracking the Chemical Evolution of Hydrocarbons Through Carbon Grain Supply in Protoplanetary Disks

The Astrophysical Journal
The gas present in planet-forming disks typically exhibits strong emission features of abundant carbon and oxygen molecular carriers. In some instances, protoplanetary disks show an elevated C/O ratio above interstellar values, which leads to a rich ...
Eshan Raul, Felipe Alarcón, Edwin A. Bergin   +2 more
doaj   +1 more source

About compiled catalogue of spectroscopic determined chemical abundances for stars with accurate parallaxes. Magnesium [PDF]

, 2005
T. V. Borkova, В. А. Марсаков
openalex   +1 more source

High-precision chemical abundances of Galactic building blocks. The distinct chemical abundance sequence of Sequoia

, 2021
Tadafumi Matsuno, Helmer H. Koppelman, A. Helmi, Wako Aoki, Miho N. Ishigaki, Takuma Suda, Zhen Yuan, Kohei Hattori   +7 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

What Can We Learn from the Nitrogen Abundance of High-z Galaxies?

The Astrophysical Journal
We present measurements of the gas-phase oxygen and nitrogen abundances obtained by applying the direct method to JWST NIRspec R  ∼ 1000 spectroscopy for six galaxies at redshift greater than 3.
Massimo Stiavelli, Takahiro Morishita, Marco Chiaberge, Nicha Leethochawalit, Colin Norman, Massimo Ricotti, Guido Roberts-Borsani, Tommaso Treu, Eros Vanzella, Rosemary F. G. Wyse, Yechi Zhang, Kit Boyett   +11 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

High-Resolution Chemical Abundances of the Nyx Stream [PDF]

, 2022
Shuyu Wang, Lina Necib, Alexander P. Ji, Xiaowei Ou, Mariangela Lisanti, Mithi A. C. de los Reyes, Allison L. Strom, Mimi Truong   +7 more
openalex   +1 more source