Results 151 to 160 of about 4,406,721 (399)

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

The connection between the Galactic halo and ancient Dwarf Satellites

, 2017
We explore the hypothesis that the classical and ultra-faint dwarf spheroidal satellites of the Milky Way have been the building blocks of the Galactic halo by comparing their [O/Fe] and [Ba/Fe] versus [Fe/H] patterns with the ones observed in Galactic ...
Matteucci, F., Romano, D., Spitoni, E., Vincenzo, F.   +3 more
core   +1 more source

Stellar parameters and chemical abundances of 223 evolved stars with and without planets [PDF]

, 2014
Aims. We present fundamental stellar parameters, chemical abundances, and rotational velocities for a sample of 86 evolved stars with planets (56 giants; 30 subgiants), and for a control sample of 137 stars (101 giants; 36 subgiants) without planets. The
E. Jofr'e, R. Petrucci, C. Saffe, L. Saker, E. A. D. L. Villarmois, C. Chavero, M. G'omez, P. Mauas   +7 more
semanticscholar   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Stokes $IQUV$ magnetic Doppler imaging of Ap stars - III. Next generation chemical abundance mapping of Alpha 2 CVn [PDF]

, 2014
In a previous paper we presented an updated magnetic field map for the chemically peculiar star Alpha 2 CVn using ESPaDOnS and Narval time-resolved high-resolution Stokes $IQUV$ spectra. In this paper we focus on mapping various chemical element distributions on the surface of Alpha 2 CVn.
arxiv   +1 more source

The building up of the disk galaxy M33 and the evolution of the metallicity gradient

, 2007
The evolution of radial gradients of metallicity in disk galaxies and its relation with the disk formation are not well understood. Theoretical models of galactic chemical evolution make contrasting predictions about the time evolution of metallicity ...
Aller, Arnett, Aubert, Beaulieu, Block, Block, Brooks, Bullock, Chabrier, Chang, Chiappini, Chiappini, Chiappini, Chieffi, Ciardullo, Ciardullo, Corbelli, Corbelli, Crockett, D. Galli, Davidge, de Boer, Devereux, Diaz, E. Corbelli, Elmegreen, Engargiola, Ferrini, Ferrini, Ferrini, Ferrini, Freedman, Freeman, Friel, Gallagher, Galletti, Garnett, Gavilán, Goetz, Henry, Henry, Henry, Herrero, Herwig, Heyer, Hippelein, Hirschi, Holmberg, Hoopes, Hou, Israel, Kennicutt, Kennicutt, Kennicutt, Keres, Kim, Koeppen, Kroupa, Kroupa, Kwitter, L. Magrini, Maciel, Maciel, Maciel, Maciel, Magrini, Magrini, Magrini, Marigo, McCarthy, McConnachie, Mollà, Mollà, Mollà, Monteverde, Monteverde, Naab, Newton, Portinari, Portinari, Regan, Richer, Romano, Rowe, Salpeter, Sandage, Scalo, Scalo, Smith, Stanghellini, Stephens, Talbot, Thielemann, Tiede, Tinsley, Tosi, Urbaneja, Venn, Vílchez, Wakker, Westmeier, Willner, Woosley, Wyse, Young   +104 more
core   +1 more source

Chemical abundances in bright giants of the globular cluster M62 (NGC 6266) [PDF]

, 2014
With the exception of Terzan 5, all the Galactic globular clusters that possess significant metallicity spreads, such as ω Cen and M22, are preferentially the more luminous clusters with extended horizontal branches. Here we present radial velocities and
D. Yong, A. Brito, G. Costa, J. Alonso-García, A. Karakas, M. Pignatari, I. Roederer, W. Aoki, C. Fishlock, F. Grundahl, J. Norris   +10 more
semanticscholar   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Improving the determination of chemical abundances in planetary nebulae [PDF]

arXiv, 2016
Planetary nebulae are the products of the evolution of low and intermediate mass stars. The chemical property studies of these objects give important information about the elemental abundances as He, O, Ne, Ar, S and their modifications associated with the evolution of the progenitor stars.
arxiv  

Chemical Abundances of the Leo II Dwarf Galaxy

, 2008
We use previously-published moderate-resolution spectra in combination with stellar atmosphere models to derive the first measured chemical abundance ratios in the Leo II dSph galaxy.
Azzopardi, Chou, Cohen, Coleman, David O. Cook, Demers, Dolphin, Dotter, Fulbright, Fulbright, Gratton, Helmi, Hinkle, Ivans, Koch, Koch, Koch, Lee, Majewski, Majewski, Marin-Franch, Matthew D. Shetrone, Michael H. Siegel, Milone, Palma, Piotto, Pritzl, Ramírez, Ramírez, Shetrone, Shetrone, Shetrone, Siegel, Siegel, Siegel, Simon, Sneden, Sohn, Sollima, Swope, Tammy Bosler, Thévenin, Tolstoy, Venn, Walker   +44 more
core   +1 more source