Results 101 to 110 of about 7,423,179 (348)

Chemically modified polystyrene co-loaded with antimicrobial agents

, 2021
Youngdae Koh, Hui Leng Choo, Yin How Wong, Chai Hong Yeong   +3 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Physical and chemical methods for enhancing rapid detection of viruses and other agents [PDF]

, 1993
John H. Hughes
openalex   +1 more source

Metal-Organic Frameworks as Efficient Sorbents for Solid-Phase Extraction of Chemical Warfare Agents, Their Simulants, and Degradation Products in Water Samples

, 2023
J. S. Wozniak, D. Zasada, Barbara Szczęśniak, J. Choma, Jakub Nawała, Stanisław Popiel   +5 more
openalex   +1 more source

Utilization of Pharmaceutical Technology Methods for the Development of Innovative Porous Metasilicate Pellets with a Very High Specific Surface Area for Chemical Warfare Agents Detection [PDF]

, 2021
Jiří Zeman, Sylvie Pavloková, David Vetchý, Adam Staňo, Z. Moravec, Lukáš Matějovský, Vladimír Pitschmann   +6 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Recent Advances in the Application of Natural Coagulants for Sustainable Water Purification

Eng
Growing pressure from shrinking freshwater supplies and worsening pollution has heightened the demand for more effective water treatment solutions, especially those that promote reuse.
Davide Frumento, Ştefan Ţălu
doaj   +1 more source

[Chemical warfare agents].

Lijecnicki vjesnik, 1992
In this article a chemical weapons are reviewed. Most important groups and some of the agents are presented as well as the mechanism of their action, symptoms and therapy.
Z, Lacković, M, Salković-Petrisić, N, Mitrović, A, Horvat   +3 more
openaire   +1 more source