Results 51 to 60 of about 2,136,869 (259)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Strecker degradation products of aspartic and glutamic acids and their amides

Czech Journal of Food Sciences, 2001
Aspartic and glutamic acids, asparagine and glutamine were oxidised with either potassium peroxodisulphate or glyoxal. Nonvolatile products were derivatised and analysed by GC/FID and GC/MS.
J. Rössner, J. Velíšek, F. Pudil, J. Davídek   +3 more
doaj   +1 more source

miR-454 suppresses the proliferation and invasion of ovarian cancer by targeting E2F6

Cancer Cell International, 2020
Background The aberrant expression of microRNA-454 (miR-454) has been confirmed to be involved in the development of cancers. However, the functional role of miR-454 in the progression of ovarian cancer remains unclear.
Yunhe An, Jun Zhang, Xiaoyan Cheng, Baoming Li, Yanjie Tian, Xiaoli Zhang, Fangqi Zhao   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Chemical analysis [PDF]

Nature, 2001
John F. Kennedy, Michael Thorley
openaire   +3 more sources

Native N-glycome profiling of single cells and ng-level blood isolates using label-free capillary electrophoresis-mass spectrometry

Nature Communications
The development of reliable single-cell dispensers and substantial sensitivity improvement in mass spectrometry made proteomic profiling of individual cells achievable.
Anne-Lise Marie, Yunfan Gao, Alexander R. Ivanov   +2 more
doaj   +1 more source

Evaluation of Ethanol Grade on the Robustness of Acid Number Determination in Fish Oil

Indonesian Journal of Chemical Analysis
The robustness evaluation of the acid number analysis method in fish oil was carried out to see the effect of the type of ethanol used as a solvent in the titration process. The types of ethanol used in this study were pro analysis grade, pharma and food
Tri Esti Purbaningtias, Sandy
doaj   +1 more source

Determination of astringent taste in model solutions and in beverages

Czech Journal of Food Sciences, 2001
The astringent taste is important for the sensory quality of beverages. Perception thresholds of two important astringent compounds - tannic acid and (+)-catechin were determined using two procedures.
H. Valentová, S. Škrovánková, Z. Panovská, J. Pokorný   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Water-insensitive NIR-I-to-NIR-I down-shifting nanoparticles enable stable biomarker detection at low power thresholds in opaque aqueous environments

Light: Science & Applications
Luminescence quenching in aqueous environments poses a challenge for practical applications. Lanthanide-doped up-conversion nanoparticles (UCNPs), representative of near-infrared (NIR)-emitting phosphors, typically utilize Yb3+ ions as sensitizers ...
Dongkyu Kang, Suyeon Kim, Yeongchang Goh, Minseo Kim, Sun-Hak Lee, Jung-Hoon Kwon, Sang Hwan Nam, Joonseok Lee   +7 more
doaj   +1 more source