From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Application of digital twins for simulation based tailoring of laser induced graphene
In the era of man–machine interfaces, digital twins stand as a key technology, offering virtual representations of real-world objects, processes, and systems through computational models.
José Carlos Santos-Ceballos +3 more
doaj +1 more source
Changes during the extrusion of semolina in mixture with sugars
Wheat semolina and its mixtures with 5% glucose, fructose of sucrose were processed in a sigle screw extruder at the maximum temperature of 140°C and the processing time of 30 s.
A. Farouk Mansour +3 more
doaj +1 more source
Quality Assessment of Summer and Autumn Carrots from a Biodynamic Breeding Project and Correlations of Physico-Chemical Parameters and Features Determined by Picture Forming Methods [PDF]
Introduction: Assessment of product quality is of special significance in organic farming and includes the supervision of crop quality in different growing systems (e.g., Fleck et al. 1998) and the characterisation of different cultivars.
Bauer, D. +3 more
core
Chemical composition of AY Ceti: A flaring, spotted star with a white dwarf companion [PDF]
The detailed chemical composition of the atmosphere AY Cet (HD 7672) is determined from a high-resolution spectrum in the optical region. The main atmospheric parameters and the abundances of 22 chemical elements, including key species such as 12C, 13C ...
Alonso +39 more
core +1 more source
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
Browning reactions between oxidised vegetable oils and amino acids
Browning reactions of oxidised lipids with amino acids were studied in mixtures of refined soybean or rapeseed oil with alanine, valine, lysine, serine, cystine, cysteine, methionine, proline, and tryptophan.
B. E Hutapea +5 more
doaj +1 more source
Motif Analysis for Small-Number Effects in Chemical Reaction Dynamics
The number of molecules involved in a cell or subcellular structure is sometimes rather small. In this situation, ordinary macroscopic-level fluctuations can be overwhelmed by non-negligible large fluctuations, which results in drastic changes in ...
Kaneko, Kunihiko +2 more
core +1 more source
Analysis of Physical and Chemical Composition of Sweet Orange (Citrus sinensis) Peels [PDF]
Sweet orange is one of the most common fruits in the World. The waste generated from the fruits needs to be put into a beneficial use. In this study some physical and chemical properties of the primary waste of sweet orange was investigated.
Ajayi, O. O. (Olabode) +3 more
core +1 more source
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source

