Results 111 to 120 of about 2,829,330 (224)
Hepatology Communications, 2019 The U.S. Drug Induced Liver Injury Network assayed the contents of herbal and dietary supplements collected from patients enrolled into its prospective study.
Victor Navarro +8 more
doaj +1 more source
Protective effect of human serum amyloid P on CCl4-induced acute liver injury in mice. [PDF]
, 2017 Human serum amyloid P (hSAP), a member of the pentraxin family, inhibits the activation of fibrocytes in culture and inhibits experimental renal, lung, skin and cardiac fibrosis.
Bao, Xiaoli +12 more
core +2 more sources
Three-dimensional cell culture model for hepatocytes opens a new avenue of real world research on liver [PDF]
arXiv, 2019 3-demensional (3D) culture model is a valuable in vitro tool to study liver biology, metabolism, organogenesis, tissue morphology, drug discovery and cell-based assays. Compelling evidence suggests that cells cultured in 3D model exhibit superior liver-specific functions over the conventional 2-dimentional (2D) culture in evaluating hepatobiliary drug ...
arxiv
Modulation of DMBA- induced biochemical and histopathological changes by Syzygium cumini seed extract during skin carcinogenesis [PDF]
, 2011 Aim & Method: The current study was designed to elucidate the protective effect of Syzygium cumini seed extract (SCE) on skin carcinogenesis induced by a single topical application of 7,12-dimethylbenz(a)anthracene (100 μg/100 μl of acetone) and 2 weeks ...
Jyoti Parmar , Priyanka Sharma , Preeti Verma , Priyanka Sharma , P.K.Goyal , Int J Cur Biomed Phar Res.
core
The role of autophagy in liver epithelial cells and its Impact on systemic homeostasis [PDF]
, 2019 Autophagy plays a role in several physiological and pathological processes as it controls the turnover rate of cellular components and influences cellular homeostasis.
Facchiano, Antonio +9 more
core +1 more source
Liver Multiacinar Regenerative Nodules: Imaging Findings and Clinical Implications
Acta Médica Portuguesa, 2018 Introduction: Multiacinar regenerative nodules are benign hepatocellular nodules related to vascular disturbances of the liver. They strongly resemble conventional focal nodular hyperplasia but are connected to different clinical settings, typically ...
Henrique Donato +5 more
doaj +1 more source
Predicting Drug-Induced Hepatotoxicity Using QSAR and Toxicogenomics Approaches [PDF]
, 2011 Quantitative Structure-Activity Relationship (QSAR) modeling and toxicogenomics are used independently as predictive tools in toxicology. In this study, we evaluated the power of several statistical models for predicting drug hepatotoxicity in rats using
Fourches, Denis +12 more
core +2 more sources
Annals of Hepatology, 2019 Introduction and Objectives: Although hepatotoxicity accounts for 10% of adverse drug reactions, it remains poorly understood and underreported. This study aimed to summarize case reports of herb- and drug-induced liver injury in Brazil.
Matheus William Becker +3 more
doaj
BMC Complementary and Alternative Medicine, 2017 Background Volatile oils from Artemisiae argyi folium (VOAAF) is reported with hepatotoxicity, but the underlying mechanism is still unclear. Methods In the present study this molecular mechanism was explored with the Ingenuity Pathway Analysis (IPA ...
Hongjie Liu +8 more
doaj +1 more source
Genetic and Immune Predictors for Hypersensitivity Syndrome to Antiepileptic Drugs [PDF]
, 2011 Hypersensitivity syndrome reactions (HSR) to antiepileptic drugs (AED) are associated with severe clinical cutaneous adverse reactions (SCAR).Our aims are: to assess HSRs to AEDs using the in vitro lymphocyte toxicity assay (LTA) in patients who ...
Lawrence Cohen +3 more
core +1 more source