Results 1 to 10 of about 8,062 (114)

Clinical management of patients with drug-induced liver injury (DILI). [PDF]

United European Gastroenterol J, 2021
Björnsson ES.
europepmc   +2 more sources

Biomarkers of idiosyncratic drug-induced liver injury (DILI) - a systematic review. [PDF]

Expert Opin Drug Metab Toxicol, 2021
Atallah E, Freixo C, Alvarez-Alvarez I, Cubero FJ, Gerbes AL, Kullak-Ublick GA, Aithal GP.   +6 more
europepmc   +2 more sources

Metabolomic analysis to discriminate drug-induced liver injury (DILI) phenotypes. [PDF]

Arch Toxicol, 2021
Quintás G, Martínez-Sena T, Conde I, Pareja Ibars E, Kleinjans J, Castell JV.   +5 more
europepmc   +2 more sources

Idiosyncratic Drug-Induced Liver Injury (DILI) and Herb-Induced Liver Injury (HILI): Diagnostic Algorithm Based on the Quantitative Roussel Uclaf Causality Assessment Method (RUCAM). [PDF]

Diagnostics (Basel), 2021
Teschke R, Danan G.
europepmc   +2 more sources

Drug-Induced Liver Injury in Tuberculosis: Mechanisms of Development and Diagnostic Methods

Juvenis Scientia, 2023
The review article discusses modern aspects of drug-induced liver injury (DILI) in patients with tuberculosis who are receiving etiotropic therapy. The main mechanisms of DILI, including toxic and idiosyncratic types, are described, as well as their ...
D. S. Sukhanov, E. V. Timofeev, Yu. S. Alekseeva, D. Yu. Azovtsev   +3 more
doaj   +1 more source

Role of Corticosteroids in Drug-Induced Liver Injury. A Systematic Review

Frontiers in Pharmacology, 2022
Introduction: Apart from cessation of the implicated agent leading to drug-induced liver injury (DILI), there is no standard therapy for DILI. Corticosteroids have been used in DILI, although their efficacy is unclear.
Einar S. Björnsson, Einar S. Björnsson, Vesna Vucic, Guido Stirnimann, Mercedes Robles-Díaz   +4 more
doaj   +1 more source

Tandem mass tag-based quantitative proteomic profiling identifies candidate serum biomarkers of drug-induced liver injury in humans

Nature Communications, 2023
Diagnosis of rare, unpredictable, drug-induced liver injury (DILI) is a significant challenge for patients, clinicians, and drug development. Here, the authors discover, evaluate, and validate potential blood biomarkers to diagnose DILI and distinguish ...
Kodihalli C. Ravindra, Vishal S. Vaidya, Zhenyu Wang, Joel D. Federspiel, Richard Virgen-Slane, Robert A. Everley, Jane I. Grove, Camilla Stephens, Mireia F. Ocana, Mercedes Robles-Díaz, M. Isabel Lucena, Raul J. Andrade, Edmond Atallah, Alexander L. Gerbes, Sabine Weber, Helena Cortez-Pinto, Andrew J. Fowell, Hyder Hussaini, Einar S. Bjornsson, Janisha Patel, Guido Stirnimann, Sumita Verma, Ahmed M. Elsharkawy, William J. H. Griffiths, Craig Hyde, James W. Dear, Guruprasad P. Aithal, Shashi K. Ramaiah   +27 more
doaj   +1 more source

Case of Ibuprofen-Induced Liver Injury

Annals of Internal Medicine: Clinical Cases, 2023
Drug-induced liver injury (DILI) resulting from nonsteroidal anti-inflammatory drugs (NSAIDs) is a rare phenomenon; however, several cases have been reported in the literature and the LiverTox database.
Kirsten Wong, Beda Cha, Simon Wu
doaj   +1 more source

Drug-induced liver injury (DILI) - mechanisms and diagnostic [PDF]

Farmacja Polska, 2022
The drug-induced liver injury (DILI) is one of the leading causes of the liver disease in developed countries. These injuries may be the result of constant drug hepatotoxicity or idiosyncrasy associated with the drug or its metabolite.
Marta Małysz, Aleksandra Więcek, Małgorzata Piechaczek, Lucyna Beata Pomierny-Chamioło   +3 more
doaj   +1 more source

Endoplasmic Reticulum Stress and Mitochondrial Stress in Drug-Induced Liver Injury

Molecules, 2023
Drug-induced liver injury (DILI) is a widespread and harmful disease closely linked to mitochondrial and endoplasmic reticulum stress (ERS). Globally, severe drug-induced hepatitis, cirrhosis, and liver cancer are the primary causes of liver-related ...
Sisi Pu, Yangyang Pan, Qian Zhang, Ting You, Tao Yue, Yuxing Zhang, Meng Wang   +6 more
doaj   +1 more source