Results 131 to 140 of about 2,829,330 (224)

Simulation-calibration testing for inference in Lasso regressions [PDF]

arXiv
We propose a test of the significance of a variable appearing on the Lasso path and use it in a procedure for selecting one of the models of the Lasso path, controlling the Family-Wise Error Rate. Our null hypothesis depends on a set A of already selected variables and states that it contains all the active variables.
arxiv  

Refining and replacing models of hepatocytes and periportal fibrosis [PDF]

, 2014
PhD ThesisThe liver plays an important role in drug toxicity, in part through its significant expression of drug-metabolising enzymes. For this reason, liver cells are often used in toxicity screening.
Probert, Philip Michael Evan
core  

Glycosaminoglycans and Glycosaminoglycan Mimetics in Cancer and Inflammation [PDF]

, 2019
Glycosaminoglycans (GAGs) are a class of biomolecules expressed virtually on all mammalian cells and usually covalently attached to proteins, forming proteoglycans.
Morla, Shravan
core   +1 more source

Understanding Immune Dynamics in Liver Transplant Through Mathematical Modeling [PDF]

arXiv
Liver transplant can be a life-saving procedure for patients with end-stage liver disease. With the introduction of modern immunosuppressive therapies, short-term survival has significantly improved. However, long-term survival has not substantially improved in decades.
arxiv  

Comparison of the Postoperative Liver Function Between Total Intravenous Anesthesia and Inhalation Anesthesia in Patients with Preoperatively Elevated Liver Transaminase Levels: A Retrospective Cohort Study

Therapeutics and Clinical Risk Management, 2020
Seok Kyeong Oh, Byung Gun Lim, Young Sung Kim, Seong Shin Kim Department of Anesthesiology and Pain Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Republic of KoreaCorrespondence: Byung Gun Lim Email bglim9205 ...
Oh SK, Lim BG, Kim YS, Kim SS
doaj  

Integration of human cell lines gene expression and chemical properties of drugs for Drug Induced Liver Injury prediction

, 2020
Wojciech Lesiński, Krzysztof Mnich, Agnieszka Kitlas Golińska, Witold R. Rudnicki   +3 more
openalex   +1 more source

Surgical Workflow Recognition and Blocking Effectiveness Detection in Laparoscopic Liver Resections with Pringle Maneuver [PDF]

AAAI 2025
Pringle maneuver (PM) in laparoscopic liver resection aims to reduce blood loss and provide a clear surgical view by intermittently blocking blood inflow of the liver, whereas prolonged PM may cause ischemic injury. To comprehensively monitor this surgical procedure and provide timely warnings of ineffective and prolonged blocking, we suggest two ...
arxiv  

Drug-induced liver injury in children: A nationwide cohort study from China

JHEP Reports
Background & Aims: Currently, there is limited knowledge on the clinical profile of drug-induced liver injury (DILI) in Chinese children. We aimed to assess the clinical characteristics, suspected drugs, and outcomes associated with pediatric DILI in
Rongtao Lai, Xinjie Li, Jie Zhang, Jun Chen, Changqing Yang, Wen Xie, Yuecheng Yu, Xiaoyan Guo, Xinrong Zhang, Guoliang Lu, Xi’an Han, Qing Xie, Chengwei Chen, Tao Shen, Yimin Mao   +14 more
doaj  

Clinical factors predicting drug-induced liver injury due to flucloxacillin

Drug, Healthcare and Patient Safety, 2018
Mikaela Lindh,1 Pär Hallberg,1 Qun-Ying Yue,2 Mia Wadelius1 1Department of Medical Sciences, Clinical Pharmacology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden; 2Swedish Medical Products Agency, Uppsala, Sweden Objectives ...
Lindh M, Hallberg P, Yue QY, Wadelius M
doaj  

Hepatotoxicity evaluation method through multiple-factor analysis using human pluripotent stem cell derived hepatic organoids. [PDF]

Sci Rep
Shin DS, Yang JY, Jeong HN, Mun SJ, Kim H, Son MJ, Bae MA.   +6 more
europepmc   +1 more source