Results 181 to 190 of about 211,350 (240)

Effects of different drying methods on the quality of <i>Lycium barbarum</i>: Focus on the carotenoids and polysaccharides. [PDF]

Food Chem X
Jian Y, Wang N, Han Z, Li Y, Huo T, Gong Y, Di D, Ma L, Pei D, Liu J.   +9 more
europepmc   +1 more source

Probing mitochondrial peroxynitrite biogenesis by a N-morpholinoarylimine-based iridium(III) complex in drug-induced liver cells. [PDF]

Redox Biol
Kong L, Wang L, Zhang Z, Ye L, Shiu-Hin Chan D, Wong CY, Wang J, Leung CH, Wang W.   +8 more
europepmc   +1 more source

Green PEGylated-Sily@ZnFe2O4 nanocomposites for amelioration of ROS and DNA damage in rat liver. [PDF]

Sci Rep
Waqas M, Saif MS, Batool S, Ahmed MM, Tariq T, Hussain R, Mustafa G, Ghorbanpour M, Hasan M.   +8 more
europepmc   +1 more source

Exocarpium Citri Grandis ameliorates alcoholic liver disease by modulation of hepatic lipid metabolism and iron homeostasis. [PDF]

Chin Med
Li YJ, Zhang YX, Xu S, Qin MC, Deng GH, Li JJ, Shen XF, Guo H, Liao YX, Zhou CY, Huang SH, Liu MH, Zhao WX, Gao L.   +13 more
europepmc   +1 more source

Pharmacological Effects and Mechanisms of Tanshinone IIA in Bone Injury Repair. [PDF]

Pharmaceuticals (Basel)
Hu W, Si Y, Wen X, Lin D, Yu Z, Xie X, Xu J.   +6 more
europepmc   +1 more source

Dynamic chemical labelling accurately quantifies microRNA-122 and reveals the presence of isomiRs that compromise PCR-based analysis in drug-induced liver injury

, 2019
Dear, James, López-Longarela, Barbara, Morrison, Emma, Tranter, John David, Ilyine, Hugh, Duffy, David, Diaz-Mochon, Juan   +6 more
openaire   +1 more source

Ferroptosis: action and mechanism of chemical/drug-induced liver injury

Drug and Chemical Toxicology, 2023
Drug-induced liver injury (DILI) is characterized by hepatocyte injury, cholestasis injury, and mixed injury. The liver transplantation is required for serious clinical outcomes such as acute liver failure. Current studies have found that many mechanisms were involved in DILI, such as mitochondrial oxidative stress, apoptosis, necroptosis, autophagy ...
Li Zeng, Xueli Jin, Qing-Ao Xiao, Wei Q. Jiang, Shanshan Han, Jin Chao, Ding Zhang, Xuan Xia, Decheng Wang   +8 more
semanticscholar   +4 more sources

Chemical Probes for drug-induced Liver Injury Imaging

Future Medicinal Chemistry, 2020
Drug-induced liver injury (DILI) has been a long-standing concern of modern medicine, and the single most frequent reason for drug nonapprovals and postapproval restrictions or withdrawals. Chemical probes for early diagnosis of DILI has triggered a tremendous interest in the field of molecular imaging.
Jiang Tao, Pengfei Rong, Wei Wang
semanticscholar   +5 more sources

A comprehensive review of Dynamic Chemical Labelling on Luminex xMAP technology: a journey towards Drug-Induced Liver Injury testing

Analytical Methods, 2023
By integrating Dynamic Chemical Labelling (DCL) with Luminex xMAP technology, it becomes feasible to analyse miRs through single- and multi-plex assays, as well as to simultaneously analyse proteins and miRs.
Antonio Marín-Romero, Salvatore Pernagallo   +1 more
semanticscholar   +4 more sources

Mechanisms of the hepatoprotective effects of tamoxifen against drug-induced and chemical-induced acute liver injuries

Toxicology and Applied Pharmacology, 2012
Although estrogen receptor (ER)α agonists, such as estradiol and ethinylestradiol (EE2), cause cholestasis in mice, they also reduce the degree of liver injury caused by hepatotoxicants as well as ischemia-reperfusion. The functional mechanisms of ERα have yet to be elucidated in drug-induced or chemical-induced liver injury.
Yukitaka Yoshikawa, Taishi Miyashita, Satonori Higuchi, Koichi Tsuneyama, Shinya Endo, Tohru Tsukui, Yasuyuki Toyoda, Tatsuki Fukami, Miki Nakajima, Tsuyoshi Yokoi   +9 more
openalex   +4 more sources