Results 211 to 220 of about 198,086 (334)

Bioassay-guided isolation of hepatoprotective lignans from <i>Vernonia cinerea</i>: DeepSAT-driven structural elucidation and predictive mechanistic insights against drug-induced liver injury. [PDF]

RSC Med Chem
Li M, Zhang MK, Song X, Zhong YT, Gui MA, Ping J, Cai YS, Yuan RY.   +7 more
europepmc   +1 more source

Vascularized and Perfusable Human Heart‐on‐a‐Chip Model Recapitulates Aspects of Myocardial Ischemia and Enables Analysis of Nanomedicine Delivery

Advanced Materials, EarlyView.
This novel 3D human ischemic heart‐on‐a‐chip, with perfusable vasculature directly interfaced with myocardial tissue, replicates key aspects of ischemic heart injury. It also demonstrates the targeted delivery and therapeutic efficacy of cardiac homing peptide‐conjugated liposomes, validating the platform for drug and nanomedicine screening in ...
Junyoung Kim, Xuening Zhang, Richard Wang, Adrian Najer, Qiao You Lau, Ana Cammack‐Najera, Jang Ah Kim, Yoo Kyung Kang, Ruoxiao Xie, Hyemin Kim, Kai Xie, Hyeonji Lim, Tae‐Eun Park, Jinmyoung Joo, Molly M. Stevens   +14 more
wiley   +1 more source

Hepatoprotective Effect of Ethanolic Extract of Cnestis ferruginea Roots on Carbon tetrachloride-Induced Liver Damage in Male Rats

Journal of Applied Sciences and Environmental Management
Hepatoprotection or antihepatotoxicity is the ability of an agent or chemical to prevent damage to the liver. These hepatoprotective agents mitigate the liver injury caused by the hepatotoxic agents.
E. O. Okoro
doaj  

Autoimmune Hepatitis and Drug-Induced Liver Injury in Japan. [PDF]

J Clin Med
Nishikawa H, Kim SK, Asai A.
europepmc   +1 more source

Plaque‐Targeted Delivery of Fluoride‐Free MXene Nanozyme for Alleviating Atherosclerosis via Sonocatalytic Therapy

Advanced Materials, EarlyView.
This work has developed a dual enzyme‐mimicking and ultrasound‐responsive Nb2C‐Pt@HA‐PEG nanozyme. ROS‐eliminating and anti­inflammatory capability of Nb2C‐Pt@HA‐PEG under US irradiation are demonstrated on macrophages and endothelial cells in vitro. Nb2C‐Pt@HA‐PEG‐mediated sonocatalytic therapy exerts an outstanding anti‐atherosclerosis efficacy by ...
Qianqian Bai, Xinyue Lao, Sin‐Yi Pang, Yifei Zhao, Yuan Liu, Xiao Yu Tian, Jianhua Hao   +6 more
wiley   +1 more source

Nimbolide Targeting SIRT1 Protects Against Acetaminophen-Induced Acute Liver Injury by Regulating Oxidative Stress and Endoplasmic Reticulum Stress. [PDF]

Pharmacol Res Perspect
Ba J, Lin Y, Zhang J, Wang Y, Wu B.
europepmc   +1 more source

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

Advanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding, Bing Liu, Andreas Peil, Sisi Fan, Jie Chao, Na Liu   +5 more
wiley   +1 more source

Local intratracheal delivery of perfluorocarbon nanoparticles to lung cancer demonstrated with magnetic resonance multimodal imaging [PDF]

, 2018
Chen, Junjie, Lanza, Gregory M, Schmieder, Anne H, Shen, Baozhong, Stacy, Allen J, Sun, Xilin, Wang, Chunan, Wang, Kai, Wang, Xiance, Wen, Xiaofei, Williams, Todd, Wu, Lina, Zhang, Huiying   +12 more
core   +2 more sources

The multiple mechanisms and modes of cell death after acetaminophen overdose. [PDF]

Explor Dig Dis
Jaeschke H, Ramachandran A.
europepmc   +1 more source

Mitochondrial Transplantation via Magnetically Responsive Artificial Cells Promotes Intracerebral Hemorrhage Recovery by Supporting Microglia Immunological Homeostasis

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou, Jinhui Zang, Yuxuan Qian, Qiang Zhang, Yifan Wang, Tingting Yao, Hongyu Yan, Kai Zhang, Xiaojun Cai, Lixian Jiang, Yuanyi Zheng   +10 more
wiley   +1 more source