Results 211 to 220 of about 103,692 (253)

ROS‐Responsive Eye Drop for Controlled Release of 20‐Deoxyingenol Improves Diabetic Corneal Healing by Activating Macrophage Autophagy and Metabolic Reprogramming

Advanced Science, EarlyView.
Schematic illustration of ROS‐responsive TSPBA‐PVA microspheres loaded with 20‐deoxyingenol (TP/20‐DOI) for diabetic corneal wound healing: (a) fabrication and ROS‐triggered release; (b) autophagy activation and metabolic reprogramming in macrophages; (c) suppression of macrophage‐derived CXCL3/CXCL5, attenuation of neutrophil infiltration, and ...
Jiaxin Wu, Wanying Chen, Haijiang Qiu, Weihan Zheng, Ying Jiao, Jingheng Du, Zhudan Zhuang, Xing Hua, Jingyi Gu, Yuheng Liu, Zhaojin Li, Jingbin Xie, Hanxiao Sun, Huifei Lan, Xin Sun, Yunxia Xue, Ting Fu, Zhijie Li, Guobing Chen, Shiyu Li, Jun Liu   +20 more
wiley   +1 more source

Betaine-driven Keap1 methylation promotes p62-mediated autophagy and Nrf2 stabilization to alleviate glutathione-dependent redox dyshomeostasis in liver injury. [PDF]

Mol Biomed
Chang MH, Lee CH, Cho Y, Son RG, Lee S, Park S, Kim J, Koh YH, Cho AE, Pack SP, Seo M, Lee JH, Cha H.   +12 more
europepmc   +1 more source

Amoxicillin-Induced Drug-Induced Liver Injury Superimposed on Acute Hepatitis C Infection in a Patient With Hurler Syndrome: A Diagnostic Challenge Assessed by the Updated RUCAM. [PDF]

Case Reports Hepatol
Garg A, Seshie P, Chouthai A, Raval S, Santharaman A, Manzoor A, Broder A.   +6 more
europepmc   +1 more source

Annexin A5 Maintains Mitochondrial Integrity by Inhibiting mPTP Opening to Protect Against Acetaminophen-Induced Acute Liver Injury. [PDF]

Int J Mol Sci
Zhang X, Li W, Li L, Wang Y, Tang W, Zhang J, Hua Z.   +6 more
europepmc   +1 more source

PLGA-loaded puerarin attenuates arsenic-induced liver injury through modulation of ferroptosis, oxidative stress, inflammation, and apoptotic signaling. [PDF]

BMC Pharmacol Toxicol
Alyamani SA, Hifni BA, Alqahtani NS, Elmorsy EM, Al-Ghafari AB, Al Doghaither HA, Chatha WA, Elshopakey GE.   +7 more
europepmc   +1 more source

Towards Bayesian-based quantitative adverse outcome pathways using in vitro data from open literature and continuous variables: a case example for liver fibrosis. [PDF]

Toxicol Sci
Durnik R, Juchelkova T, Hecht H, Winkelman LMT, Beltman JB, Coumoul X, Jornod F, Audouze K, Blaha L, Bajard L.   +9 more
europepmc   +1 more source

Therapeutic Potential of Nanocurcumin in Mitigating Duloxetine-Induced Hepatic Damage: Biochemical and Histopathological Insights. [PDF]

J Biochem Mol Toxicol
Abedi H, Jahromi MJ, Mohammadzade Z, Ebrahimi B, Abdollahzadeh P, Hassannezhad A, Sheikhnia F, Jahromi HK.   +7 more
europepmc   +1 more source

Dynamic chemical labelling accurately quantifies microRNA-122 and reveals the presence of isomiRs that compromise PCR-based analysis in drug-induced liver injury

, 2019
Dear, James; id_orcid 0000-0002-8630-8625, López-Longarela, Barbara, Morrison, Emma, Tranter, John David, Ilyine, Hugh, Duffy, David, Diaz-Mochon, Juan   +6 more
openaire   +1 more source