Results 91 to 100 of about 127,539 (258)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Variability in morphological and physico-chemical traits of aonla (Emblica officinalis) genotypes collected from north-eastern region of India

open access: yesThe Indian Journal of Agricultural Sciences, 2016
Wild aonla (Emblica officinalis Gaertn.) is found growing throughout the north eastern region of India. An extensive survey was made to identify and collect the elite genotypes at different altitude to determine variability for physical and biochemical ...
A K SINGH   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Reaction kinetics of physico-chemical attributes in coconut inflorescence sap during fermentation. [PDF]

open access: yesJ Food Sci Technol, 2021
Pandiselvam R   +10 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

CHEMICAL ATTRIBUTES AND SOIL CARBON AND NITROGEN STOCKS IN PASTURES IN THE MARANHÃO AMAZON

open access: yesRevista de Agricultura Neotropical
In the eastern Amazon region, converting forests into pastureland is a common practice that quickly leads to the degradation of these areas. This study aimed to evaluate the influence of different land uses in different evaluation periods on the ...
Maycon Pedrosa Cardoso   +6 more
doaj   +1 more source

The Evaluation of Dark Chocolate-Elicited Emotions and Their Relation with Physico Chemical Attributes of Chocolate. [PDF]

open access: yesFoods, 2021
Bartkiene E   +9 more
europepmc   +1 more source

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