Results 81 to 90 of about 127,539 (258)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Influência da adubação orgânica nas propriedades químicas de um Latossolo Vermelho distrófico e na produção de matéria seca de Brachiaria brizantha cv. Marandu = The influence of organic fertilization on the chemical properties of a dystrophic Red Latosol and on the production of Brachiaria brizantha cv. Marandu dry matter

Acta Scientiarum. Agronomy, 2007
Com o objetivo de conhecer a influência da adubação orgânica naspropriedades químicas de um Latossolo Vermelho distrófico cultivado com Brachiaria brizantha cv.
José Jaime de Lima, José de Deus Viana da Mata, Raimundo Pinheiro Neto, Carlos Alberto Scapim   +3 more
doaj  

IMPACT OF SLOW DRYING IN A COLD ROOM ON COFFEE SENSORY, CHEMICAL, AND PHYSICAL PROPERTIES [PDF]

Engenharia Agrícola
This study aimed to evaluate the duplicity and synergism of slow drying and storage processes at low temperatures, using a refrigerated room under suitable conditions for coffee fruit just after harvest.
Rodrigo A. Jordan, Fabrício C. de Oliveira, Eliana J. S. Argandoña, Anamari V. A. Motomiya, Rodrigo C. Santos   +4 more
doaj   +1 more source

Soil chemical attributes in areas under conversion from forest to pasture in southern Brazilian Amazon. [PDF]

Sci Rep, 2022
de Lima AFL, Campos MCC, Martins TS, Silva GA, Brito WBM, Dos Santos LAC, de Oliveira IA, da Cunha JM.   +7 more
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Physico-Chemical Attributes of Lemon Fruits as Affected by Growing Substrate and Rootstock. [PDF]

Foods, 2022
Martínez-Nicolas JJ, Núñez-Gómez D, Lidón V, Martínez-Font R, Melgarejo P, Hernández F, Legua P.   +6 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Deciphering the response of thirteen apple cultivars for growth, fruit morphology and fruit physico-chemical attributes during different years. [PDF]

Heliyon, 2023
Ali MT, Mehraj S, Mir MS, Shah IA, Shah ZA, El-Serehy HA, Dar EA, Bhat AH, Wani SA, Fayaz U, Al-Misned FA, Shafik HM.   +11 more
europepmc   +1 more source