Results 41 to 50 of about 496,469 (302)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Modeling of chemical reaction systems with detailed balance using gradient structures [PDF]

, 2020
We consider various modeling levels for spatially homogeneous chemical reaction systems, namely the chemical master equation, the chemical Langevin dynamics, and the reaction-rate equation.
Maas, Jan, Maas, Jan ; https://orcid.org/, Mielke, Alexander   +2 more
core   +1 more source

Global DNA-methylation in quantitative epigenetics: orbitrap mass spectrometry

Frontiers in Molecular Biosciences
DNA methylation is the most common epigenetic modification in both prokaryotic and eukaryotic genomes. Here we present a method based on highly efficient acid-hydrolysis of DNA, liquid chromatography, and detection by mass spectrometry to accurately ...
Janine F. M. Otto, Georg Pohnert, Georg Pohnert, Thomas Wichard, Michael Bauer, Michael Bauer, Anne Busch, Anne Busch, Anne Busch, Nico Ueberschaar   +9 more
doaj   +1 more source

Adaptation ukrainian legislation on regulation of manufacture and use of chemicals with EU norms on the basis of partnership and cooperation agreement 1994.

Теорія і практика правознавства, 2016
The EU countries have realised necessity of a legal regulation of the chemical substances for health protection of the person and maintenance of natural balance.
О. С. Бабенко
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Evaluation of optimization methods for solving the receptor model for chemical mass balance [PDF]

Journal of the Serbian Chemical Society, 2015
Balance (CMB) model has been extensively used in order to determine source contribution for particulate matters (size diameters less than 10 μm and 2.5 μm) in the air quality analysis.
Anu N., Rangabhashiyam S., Rahul Antony, Selvaraju N.   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

(Table 5) Concentration of chemical compounds deduced from ion balance measurements on the GRIP and Dome Fuji ice cores

, 2008
(Table 5) Concentration of chemical compounds deduced from ion balance measurements on the GRIP and Dome Fuji ice ...
Yoshinori Iizuka (8008220), Steffensen, Jørgen Peder, Hondoh, Takeo, Takeo Hondoh (8008223), Sakurai, Toshimitsu, Toshimitsu Sakurai (8008217), Jørgen Peder Steffensen (6961868), Dahl-Jensen, Dorthe, Dorthe Dahl-Jensen (6975797), Horikawa, Shinichiro, Sigfus Johnson (8024414), Johnson, Sigfus, Shinichiro Horikawa (3526973), Iizuka, Yoshinori   +13 more
core   +1 more source

Approaching coupled cluster accuracy with a general-purpose neural network potential through transfer learning

Nature Communications, 2019
Computational modelling of chemical systems requires a balance between accuracy and computational cost. Here the authors use transfer learning to develop a general purpose neural network potential that approaches quantum-chemical accuracy for reaction ...
Justin S. Smith, Benjamin T. Nebgen, Roman Zubatyuk, Nicholas Lubbers, Christian Devereux, Kipton Barros, Sergei Tretiak, Olexandr Isayev, Adrian E. Roitberg   +8 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source