Results 161 to 170 of about 171,008 (291)

CRISPR‐Cas9 Genome‐Wide Screening in Paediatric Cancer: Functional Genomics for Target Discovery and the Improvement of Existing Therapies

Medicinal Research Reviews, EarlyView.
ABSTRACT CRISPR‐Cas9 genome‐wide screening has been instrumental towards identifying novel targets for drug discovery in cancer research. However, much of this research has centred specifically on adult cancers, with paediatric cancers being underserviced by current research and screening.
Steven He, Patrick Connerty, Antoine de Weck   +2 more
wiley   +1 more source

Evaluation of tumor clonality with chemical carcinogenesis in a mouse model of visualized X chromosome inactivation. [PDF]

J Toxicol Pathol
Maeda-Tateishi T, Nagata Y, Imanishi Y, Hirakawa T, Tan SS, Emoto M, Gi M.   +6 more
europepmc   +1 more source

AhR and STAT3: A Dangerous Duo in Chemical Carcinogenesis. [PDF]

Int J Mol Sci
Minacori M, Fiorini S, Perugini M, Iannetta A, Meschiari G, Chichiarelli S, Altieri F, Natali PG, Eufemi M.   +8 more
europepmc   +1 more source

Dynamic m⁶A mRNA methylation reveals the role of METTL3-m⁶A-CDCP1 signaling axis in chemical carcinogenesis. [PDF]

Oncogene, 2019
Yang F, Jin H, Que B, Chao Y, Zhang H, Ying X, Zhou Z, Yuan Z, Su J, Wu B, Zhang W, Qi D, Chen D, Min W, Lin S, Ji W.   +15 more
europepmc   +1 more source

Bridging Psychological Stress and Skin Cellular Aging: Flavonoids as a Dual‐Action Therapeutic Strategy

Phytotherapy Research, EarlyView.
ABSTRACT Psychological stress (or simply “stress”) is a major contributor to chronic disease worldwide, affecting 35% of the global population, including younger generations. Furthermore, it plays a significant role in human premature aging; hence, its detrimental effects on people's health compel us to comprehend and control the ways in which ...
Marco Duarte, Sílvia Santos Pedrosa, P. Raaj Khusial, Ana Raquel Madureira   +3 more
wiley   +1 more source

Targeting chemical carcinogenesis: α-pinene and D-limonene as chemopreventive agents against NNK/TCDD- and urethane-induced lung tumorigenesis. [PDF]

J Food Drug Anal
Huang KC, Chew VH, Chen YY, Su HJ, Chang HT, Chen RJ, Wang YJ.   +6 more
europepmc   +1 more source

Mechanisms of chemical carcinogenesis in the kidneys. [PDF]

Int J Mol Sci, 2013
Radford R, Frain H, Ryan MP, Slattery C, McMorrow T.   +4 more
europepmc   +1 more source

Phytochemical‐Based Strategies for Lung Cancer: Clinical Insights Into Pleiotropic Molecular Signaling and Therapeutic Roles

Phytotherapy Research, EarlyView.
Lung cancer (LC) remains the leading cause of global cancer‐related death. Phytochemicals from medicinal plants are increasingly being considered as potential LC treatment agents due to their multi‐targeted action, safety, and accessibility. These have anticancer properties by regulating key molecular signaling pathways.
Md. Rezaul Islam, Abdur Rauf, Happy Akter, Md. Ibrahim Khalil Al‐Imran, Md. Naeem Hossain Fakir, Gazi Kaifeara Thufa, Umme Habiba, Karjin Nahar Riya, Md. Mahfuzur Rahman, Md Sadique Hussain, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Dorota Formanowicz, Marcello Iriti   +14 more
wiley   +1 more source

Editorial: Furthering precision medicine and cancer prevention through novel insights in molecular and chemical carcinogenesis. [PDF]

Front Oncol
Bisson WH, Liby KT, Bernard JJ.
europepmc   +1 more source

Quercetin Reverses Rat Liver Preneoplastic Lesions Induced by Chemical Carcinogenesis. [PDF]

Oxid Med Cell Longev, 2017
Carrasco-Torres G, Monroy-Ramírez HC, Martínez-Guerra AA, Baltiérrez-Hoyos R, Romero-Tlalolini MLÁ, Villa-Treviño S, Sánchez-Chino X, Vásquez-Garzón VR.   +7 more
europepmc   +1 more source