Results 181 to 190 of about 83,835 (249)

Mycobacterium avium Subsp. paratuberculosis and Human Endogenous Retrovirus in Italian Patients With Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS)

Immunology, Volume 178, Issue 3, Page 417-427, July 2026.
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto, Alfredo Santovito, Gian P. Caviglia, Marta Noli, Davide Cossu, Davide G. Ribaldone, Demis Pitoni, Simona Frara, Elisa Tribocco, Chiara Rosso, Marta Guriglia, Ilaria Cossu, Pier A. Tovo, Massimiliano Bergallo, Leonardo A. Sechi   +14 more
wiley   +1 more source

Chemical Carcinogenesis [PDF]

, 2020
openaire   +1 more source

Integrated network toxicology and immune profiling identify ESR1 as a potential hub linking Benzo[a]pyrene exposure to gastric cancer risk. [PDF]

Discov Oncol
Wang C, Deng Y, Yang R.
europepmc   +1 more source

Atrophic gastritis of distinct etiologies: malignant potential in <i>Helicobacter pylori</i>-associated and autoimmune forms. [PDF]

Ann Gastroenterol
Rokkas T, Rugge M.
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, Volume 20, Issue 6, Page 1556-1590, June 2026.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, Volume 20, Issue 6, Page 1392-1397, June 2026.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

The multistep progression of areca nut-induced oral cancer: a mechanistic roadmap from pathogenesis to precision therapy. [PDF]

Life Med
Yu N, Cai W, Zhang C, Cai Q, Zhang Z, Hu Y, Sun Y, Yin K, Ren F, Chang K, Jin M, Li D, Zhang L, Wu H, Li M.   +14 more
europepmc   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, Volume 16, Issue 6, Page 1181-1196, June 2026.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Radiotherapy meets anticancer metallodrugs. [PDF]

Med Rev (2021)
Zhang S, Shen S, Li J, Fu Q, Guo Z, Liu Z.   +5 more
europepmc   +1 more source

Nature's Nanotech Warriors: The Role of Metalloproteins and Protein Cages for Environmental Remediation

Advanced Sustainable Systems, Volume 10, Issue 6, June 2026.
Cartoon representation of five major classes of metalloproteins and their brief mechanisms of bioremediation. The five classes include metallothioneins, metal‐precipitating enzymes, P.‐type ATPases, protein cages, and synthetic metalloproteins (de novo‐designed proteins/peptides for selective adsorption). These natural and engineered protein structures
Sian D'Silva, Celin Acharya, Soumyananda Chakraborti   +2 more
wiley   +1 more source