Results 91 to 100 of about 621,408 (312)

A two-stage ceramic tile grout sealing process using a high power diode laser Part I: Grout development and materials characteristics [PDF]

, 1998
Work has been conducted using a 60 W-cw high power diode laser (HPDL) in order to determine the feasibility and characteristics of sealing the void between adjoining ceramic tiles with a specially developed grout material having an impermeable enamel ...
Basov, Bourell, Buerhop, Hahn, J. Lawrence, J.T. Spencer, Kurokawa, L. Li, Li, Sivakumar, Ueki, Yu   +11 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Robust photoregulation of GABA(A) receptors by allosteric modulation with a propofol analogue. [PDF]

, 2012
Photochemical switches represent a powerful method for improving pharmacological therapies and controlling cellular physiology. Here we report the photoregulation of GABA(A) receptors (GABA(A)Rs) by a derivative of propofol (2,6-diisopropylphenol), a ...
Bruzik, Karol S, Dellal, Shlomo S, Feng, Feng, Otis, Thomas S, Pawlowski, Michal, Pepperberg, David R, Qian, Haohua, Xie, An, Yue, Lan   +8 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Application of chemical vapor generation systems to deliver constant gas concentrations for in vitro exposure to volatile organic compounds

Environ. Sci.: Processes Impacts, 2014
Schematic representation of the system design coupling a constant emission source from a diffusion vial to a gas phase in vitro exposure system (GIVES) for a direct air–liquid interface exposure to volatile organic compounds.
Ying-Hsuan Lin, Kenneth G. Sexton, Ilona Jaspers, Ya-Ru Li, Jason D. Surratt, William Vizuete   +5 more
openaire   +3 more sources

New properties of a bioinspired pyridine benzimidazole compound as a novel differential staining agent for endoplasmic reticulum and Golgi apparatus in fluorescence live cell imaging [PDF]

, 2018
Indexación: Scopus.In this study, we explored new properties of the bioinspired pyridine benzimidazole compound B2 (2,4-di-tert-butyl-6-(3H-imidazo[4,5-c]pyridine-2-yl)phenol) regarding its potential use as a differential biomarker.
Alexander Carreño, Alexander Carreño, Carolina Otero, César Zúñiga, Dayán Páez-Hernández, Felipe M. Llancalahuen, Juan A. Fuentes, Manuel Gacitúa, Marcelo D. Preite, Ramiro Arratia-Pérez, Rubén Polanco   +10 more
core   +12 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Hemimellitene (1,2,3-trimethylbenzene) in the liver, lung, kidney, and blood, and dimethylbenzoic acid isomers in the liver, lung, kidney and urine of rats after single and repeated inhalation exposure to hemimellitene

International Journal of Occupational Medicine and Environmental Health, 2016
Objectives: The aim of the study has been to explore hemimellitene distribution in blood, liver, lung and kidney as well as toxicokinetics of its elimination from blood of rats after single and repeated inhalation exposure to this compound.
Radosław Świercz, Wanda Majcherek, Wojciech Wąsowicz   +2 more
doaj   +1 more source

Chemical compounds exposure and human health: advances on the politics of chemical risk control

, 2002
Advances on the politics of chemical risk control. Observed deficiencies on the management, elimination and recirculation of chemical products. Therefore, some of the main challenges for the scientific research, environmental health, nature preservation and the environmental management are closely related to the development of validation system of the ...
Gascó, Pilar, de la Torre, Ana, de la Peña, Eduardo   +2 more
openaire   +1 more source

Transport of persistent organic pollutants across the human placenta [PDF]

, 2014
Environment International 65, 107-115 ...
Fernández-Somoano, A, Fernández-Somoano, A, Fernández-Somoano, A, Grimalt, JO, Grimalt, JO, Grimalt, JO, Tardon, A, Tardon, A, Tardon, A, Vizcaino, E   +9 more
core   +1 more source