Results 61 to 70 of about 270,239 (265)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Organizational and activational effects of estrogenic endocrine disrupting chemicals

Cadernos de Saúde Pública
Endocrine disruption is a hypothesis of common mode of action that may define a set of structurally varied chemicals, both natural and synthetic. Their common mode of action may suggest that they produce or contribute to similar toxic effects, although ...
Ellen K. Silbergeld, Jodi A. Flaws, Ken M. Brown   +2 more
doaj  

Environmental monitoring and biomarkers of exposure to styrene in chemical industry

Saúde & Tecnologia, 2018
Biomarkers of exposure to chemicals, such as styrene, allows to estimate the exposure to a particular compound by measuring the compound or it(s) metabolite(s) in body fluids.
Daniela Fernandes, Márcia Meneses, Paula Albuquerque, Miguel Barros   +3 more
doaj   +1 more source

Chemical compounds exposure and human health: advances on the politics of chemical risk control

, 2002
Advances on the politics of chemical risk control. Observed deficiencies on the management, elimination and recirculation of chemical products. Therefore, some of the main challenges for the scientific research, environmental health, nature preservation and the environmental management are closely related to the development of validation system of the ...
Gascó, Pilar, de la Torre, Ana, de la Peña, Eduardo   +2 more
openaire   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

MuCB-tabpfn: A multimodal feature fusion framework for predicting human blood concentrations of organic pollutants

Ecotoxicology and Environmental Safety
The accurate prediction of chemical concentrations in human blood is essential for evaluating health risks associated with synthetic organic pollutants. However, existing models frequently suffer from limitations such as data scarcity, incomplete feature
Jinling Liu, Xudi Pang, Huiming Cao, Yuzhen Sun, Yong Liang   +4 more
doaj   +1 more source