Results 31 to 40 of about 205,156 (280)

Synergistic Effect of L-Carnosine and Hyaluronic Acid in Their Covalent Conjugates on the Antioxidant Abilities and the Mutual Defense against Enzymatic Degradation

Antioxidants, 2022
Hyaluronic acid (Hy) is a natural linear polymer that is widely distributed in different organisms, especially in the articular cartilage and the synovial fluid. During tissue injury due to oxidative stress, Hy plays an important protective role. All the
Valeria Lanza, Valentina Greco, Eleonora Bocchieri, Sebastiano Sciuto, Rosanna Inturri, Luciano Messina, Susanna Vaccaro, Francesco Bellia, Enrico Rizzarelli   +8 more
doaj   +1 more source

From Wires to Cables: Attempted Synthesis of 1,3,5-Trifluorenylcyclohexane as a Platform for Molecular Cables [PDF]

, 2016
Multiple molecular wires braided together in a single assembly, termed as molecular cable, are promising next-generation materials for effective long-range charge transport.
Abdelwahed, Sameh H., Rathore, Rajendra, Reid, Scott, Talipov, Marat R., Thakur, Khushabu   +4 more
core   +6 more sources

Remote Access Revolution: Chemical Crystallographers Enter a New Era at Diamond Light Source Beamline I19

Crystals, 2017
Since the inception of the use of synchrotron radiation in the structural characterisation of crystalline materials by single-crystal diffraction in the late 20th century, the field has undergone an explosion of technological developments.
Natalie T. Johnson, Paul G. Waddell, William Clegg, Michael R. Probert   +3 more
doaj   +1 more source

De novo design of a homo-trimeric amantadine-binding protein. [PDF]

, 2019
The computational design of a symmetric protein homo-oligomer that binds a symmetry-matched small molecule larger than a metal ion has not yet been achieved.
Adams, Afonine, Arzt, Bale, Boyken, Campbell, Davis, Delaglio, DeRose, Dou, Dou, Emsley, Fegan, Ghirlanda, Guerrero, Hsia, Jancarik, Lee, Mallet, McCoy, Meilleur, Mills, Miyamoto, Nyanguile, Ollikainen, Otwinowski, Perez-Lloret, Polizzi, Spencer, Stankunas, Thomaston, Tinberg, Tzeng, Wang, Waudby, Winn, Zhang   +36 more
core   +2 more sources

A Novel Dual Air-Bearing Fixed-χ Diffractometer for Small-Molecule Single-Crystal X-ray Diffraction on Beamline I19 at Diamond Light Source

Crystals, 2017
Herein, we describe the development of a novel dual air-bearing fixed-χ diffractometer for beamline I19 at Diamond Light Source. The diffractometer is designed to facilitate the rapid data collections possible with a Dectris Pilatus 2M pixel-array photon-
David . R Allan, Harriott Nowell, Sarah A. Barnett, Mark R. Warren, Adrian Wilcox, Jeppe Christensen, Lucy K. Saunders, Andrew Peach, Mark T. Hooper, Ljubo Zaja, Suren Patel, Leo Cahill, Russell Marshall, Steven Trimnell, Andrew J. Foster, Trevor Bates, Simon Lay, Mark A. Williams, Paul V. Hathaway, Graeme Winter, Markus Gerstel, Ron W. Wooley   +21 more
doaj   +1 more source

High-Capacity CaCO₃ Containers: The Effect of Size on Drug Loading and Interaction with Cells

Medical Sciences Forum, 2022
A series of calcium carbonate particles with sizes of 500 ± 80 and 200 ± 90 nm were obtained using mass crystallization in aqueous salt solutions by varying the reaction conditions and adding glycerol or a combination of polyethylene glycol, polysorbat ...
Tatiana Pallaeva, Alexander Mikheev, Daniil Eurov, Dmitry Kurdyukov, Victoriya Popova, Elena Dmitrienko, Roman Akasov, Daria Trushina   +7 more
doaj   +1 more source

Fifteen years of the Protein Crystallography Station: the coming of age of macromolecular neutron crystallography

IUCrJ, 2017
The Protein Crystallography Station (PCS), located at the Los Alamos Neutron Scattering Center (LANSCE), was the first macromolecular crystallography beamline to be built at a spallation neutron source.
Julian C.-H. Chen, Clifford J. Unkefer
doaj   +1 more source

Ring closing reaction in diarylethene captured by femtosecond electron crystallography [PDF]

, 2013
The photoinduced ring-closing reaction in diarylethene, which serves as a model system for understanding reactive crossings through conical intersections, was directly observed with atomic resolution using femtosecond electron diffraction.
Asano Y., Bertarelli C., Boggio-Pasqua M., Carole A. Morrison, Cheng Lu, Chergui M., Clark S. J., Collet E., Coppens P., Dudek R. C., Dwyer J. R., Eichberger M., Erasmus N., Ern J., Ern J., Ern J., Ernstorfer R., Fritz D. M., Gao M., Gao M., Grimme S., Hallmann J., Han T.-R. T., Hania P. R., Hania P. R., Harb M., Harb M., Hubert Jean-Ruel, Ihee H., Irie M., Irie M., Jean-Ruel H., Kobatake S., Kochman M. A., Lai Chung Liu, Meng Gao, Michal A. Kochman, Miyasaka H., Miyasaka H., Miyasaka H., Morimoto M., Okabe C., Owrutsky J. C., Perdew J. P., Poulin P. R., R. J. Dwayne Miller, Ryan R. Cooney, Schotte F., Sciaini G., Sciaini G., Shim S., Siwick B. J., Srinivasan R., Tamai N., Tani K., Techert S., Tian H., Uchida K., Vorontsov I. I.   +58 more
core   +1 more source

Review

, 2020
The chalcogen elements oxygen, sulfur, and selenium are essential constituents of side chain functions of natural amino acids. Conversely, no structural and biological function has been discovered so far for the heavier and more metallic tellurium ...
Agh R, Arai K, Baskakov IV, Creighton TE, Dittmer K, Du Vigneaud V, Janeček J, Metanis N, Musiol HJ, Muttenthaler M, Nygard B, O'Donnell ME, Welch M, Yang F   +13 more
core   +1 more source

Semax, a Copper Chelator Peptide, Decreases the Cu(II)-Catalyzed ROS Production and Cytotoxicity of aβ by Metal Ion Stripping and Redox Silencing

Bioinorganic Chemistry and Applications
Alzheimer’s disease (AD) is the most common neurodegenerative disorder associated with cognitive decline and loss of memory. It is postulated that the generation of reactive oxygen species (ROS) in Fenton-like reaction connected with Cu(II)/Cu(I) redox ...
Marianna Flora Tomasello, Maria Carmela Di Rosa, Irina Naletova, Michele Francesco Maria Sciacca, Alessandro Giuffrida, Giuseppe Maccarrone, Francesco Attanasio   +6 more
doaj   +1 more source