Results 21 to 30 of about 384,598 (248)

Educação Química no Projeto Escolar “Quixaba”: Alfabetização Científica com Enfoque CTSA no Ensino Fundamental a Partir de Temas Sociocientíficos

open access: yesOrbital: The Electronic Journal of Chemistry, 2015
The objective of this study was to analyze the pedagogical aspects of teaching chemistry in a “Quixaba” school project developed with students of Science of last year of basic school (corresponding to the third cycle), focusing CTSA.
Luciana do N. Rodrigues   +5 more
doaj   +3 more sources

Monitoring Acid–Base Titrations on Wax Printed Paper Microzones Using a Smartphone

open access: yesMicromachines, 2017
This study describes the use of a smartphone for monitoring acid–base titrations on wax printed paper microzones. An array of twelve microzones of 5 mm diameter each was wax printed on filter paper.
Sandro A. Nogueira   +4 more
doaj   +1 more source

The “Lab4treat” Outreach Experience: Preparation of Sustainable Magnetic Nanomaterials for Remediation of Model Wastewater

open access: yesMolecules, 2021
The Lab4treat experience has been developed to demonstrate the use of magnetic materials in environmental applications. It was projected in the frame of the European project Mat4Treat, and it was tested several times in front of different audiences ...
Maria Laura Tummino   +8 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

HYBRID ATOMIC ORBITALS IN ORGANIC CHEMISTRY. PART 2: CRITIQUE OF PRACTICAL ASPECTS

open access: yesQuímica Nova
The importance of hybrid atomic orbitals, in both general and organic chemistry, is reviewed. Every contemporary textbook of organic chemistry introduces the directed-valence (e.g. sp3, sp2, sp) model, but the suitability of these hybrid orbitals for use
Guy Lamoureux, John F. Ogilvie
doaj   +1 more source

A formação dos docentes de química: uma perspectiva multivariada aplicada à rede pública de ensino médio de Goiás

open access: yesQuímica Nova, 2011
This paper presents a multivariate statistical analysis as a valuable tool for educational management applied to public high school chemistry teacher formation.
Deangelis Damasceno   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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