Results 121 to 130 of about 916,473 (292)

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

open access: yesMolecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa   +13 more
wiley   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

Retracted: Oxygen Mass Transfer in an Aerated Stirred Tank with Double Impellers: A Generalized Correlation Including Spacing Impact

open access: yesInternational Journal of Chemical Engineering, 2017
International Journal of Chemical Engineering
doaj   +1 more source

Shape differentiation of steady-state reaction-diffusion problems arising in chemical engineering with non-smooth kinetics with dead core

open access: yesElectronic Journal of Differential Equations, 2017
In this paper we consider an extension of the results in shape differentiation of semilinear equations with smooth nonlinearity presented by Diaz and Gomez-Castro [8] to the case in which the nonlinearities might be less smooth.
David Gomez-Castro
doaj  

Integrating the circular economy model into the management and treatment of Fischer–Tropsch effluents—a conversion of waste to energy (biogas) opportunity

open access: yesIET Renewable Power Generation
The Fischer–Tropsch (FT) process converts coal, biomass, or natural gas into liquid hydrocarbons via syngas generation and catalytic conversion. However, FT produces byproducts and effluents with substantial environmental consequences.
Mabatho Moreroa   +2 more
doaj   +1 more source

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

open access: yesMolecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock   +10 more
wiley   +1 more source

Rule-based autocorrection of Piping and Instrumentation Diagrams (P&IDs) on graphs [PDF]

open access: yesarXiv
A piping and instrumentation diagram (P&ID) is a central reference document in chemical process engineering. Currently, chemical engineers manually review P&IDs through visual inspection to find and rectify errors. However, engineering projects can involve hundreds to thousands of P&ID pages, creating a significant revision workload.
arxiv  

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