Results 151 to 160 of about 7,951,899 (374)

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

Integrating the circular economy model into the management and treatment of Fischer–Tropsch effluents—a conversion of waste to energy (biogas) opportunity

open access: yesIET Renewable Power Generation
The Fischer–Tropsch (FT) process converts coal, biomass, or natural gas into liquid hydrocarbons via syngas generation and catalytic conversion. However, FT produces byproducts and effluents with substantial environmental consequences.
Mabatho Moreroa   +2 more
doaj   +1 more source

Perfume and Flavor Engineering: A Chemical Engineering Perspective. [PDF]

open access: yesMolecules, 2021
Rodrigues AE, Nogueira I, Faria RPV.
europepmc   +1 more source

Modular microporous hydrogels formed from microgel beads with orthogonal thermo-chemical responsivity: Microfluidic fabrication and characterization. [PDF]

open access: yes, 2019
Despite the significant advances in designing injectable bulk hydrogels, the inability to control the pore interconnectivity and decoupling it from the matrix stiffness has tremendously limited the applicability of stiff, flowable hydrogels for 3D ...
Akouissi, Outman   +6 more
core  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Smart Cities Will Need Chemistry [PDF]

open access: yesScientific Bulletin of the ''Petru Maior" University of Tîrgu Mureș, 2016
A smart city is a sustainable and efficient urban centre that provides a high quality of life to its inhabitants through optimal management of its resources.
Alexandru WOINAROSCHY
doaj  

Corrigendum [PDF]

open access: yes, 2018
Nur Rokhati, Heru Susanto, Kristinah Haryani, Bambang Pramudono "Enhanced Enzymatic Hydrolysis of Chitosan by Surfactant Addition", 62(3), pp. 286-291, 2018. https://doi.org/10.3311/PPch.11142When the above article was first published online Eq.
Chemical Engineering, Periodica Polytechnica
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

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