Results 151 to 160 of about 916,473 (292)

Grand Challenges in Translational Materials Research

open access: yesFrontiers in Materials, 2017
Krisztian Kordas
doaj   +1 more source

Red social de colaboración de las universidades españolas con investigación en Ingeniería Química Scientific collaboration social network in the field of chemical engineering in spanish universities

open access: yesInvestigación Bibliotecológica: Archivonomía, Bibliotecología e Información, 2010
El presente trabajo analiza la red social de colaboración científica de las universidades españolas que realizan investigación en el área de "Ingeniería Química".
María Isabel Escalona Fernández   +2 more
doaj  

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

open access: yesMolecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric   +11 more
wiley   +1 more source

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

An application of shape differentiation to the effectiveness of a steady state reaction-diffusion problem arising in chemical engineering

open access: yesElectronic Journal of Differential Equations, 2015
In applications it is common to arrive at a problem where the choice of an optimal domain is considered. One such problem is the one associated with the steady state reaction diffusion equation given by a semilinear elliptic equation with a monotone ...
Jesus Ildefonso Diaz, David Gomez-Castro
doaj  

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