Results 141 to 150 of about 125,120,791 (279)

Computer simulation of chemical processes with electrolytes

open access: yes, 1980
Thesis (Sc.D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1980.MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE.Bibliography: leaves 254-255.by Chau-Chyun Chen.Sc ...
Chen, Chau-chyun
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NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Membrane and membrane reactor operations in chemical engineering

open access: yes, 2020
Special issue of ChemEngineering journal on "Membrane and membrane reactor operations in chemical ...
Iulianelli A
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Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

45 YEARS OF CHEMICAL ENGINEERING IN THE UNIVERSITY CITY OF CLUJ-NAPOCA 1971-2016. LANDMARKS ON THE ESTABLISHMENT, DEVELOPMENT AND AFFIRMATION OF CHEMICAL ENGINEERING EDUCATION IN THE UNIVERSITARY CITY OF CLUJ-NAPOCA

open access: yesStudia Universitatis Babes-Bolyai Chemia, 2017
In Cluj, chemistry engineering education officially begins in 1971/72 with the Polytechnic Institute (IPC) setting up an Industrial Chemistry faculty [1] with engineering and sub-engineers, specializing in Technology of Inorganic Substances (TIS) and ...
Liviu LITERAT
doaj  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Chemical and physical mechanisms of soot formation

open access: yes, 1989
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1989.Includes bibliographical references (leaves 155-164).by Julian Thomas McKinnon, Jr.Ph ...
McKinnon, Julian Thomas
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