Results 71 to 80 of about 6,312,097 (300)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
THE DEARTH OF CHEMICALLY ENRICHED WARM-HOT CIRCUMGALACTIC GAS [PDF]
The Astrophysical Journal, 2010 This is the pre-published version harvested from ArXiv.
Yao, Y +5 more
openaire +3 more sources
Reconstructing chemical enrichment pathways in disc galaxies
Astronomy & AstrophysicsContext. Phylogenetic methods, traditionally used in biology to trace the evolutionary relationships among species, are emerging as a powerful framework to reconstruct evolutionary processes in galaxies from chemical information. Aims.
Tapia-Contreras Brian +13 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The chemical enrichment of the ICM with BeppoSAX
, 2001 10 pages, 6 figures included, to appear in "Chemical Enrichment of Intracluster and Intergalactic Medium", Vulcano, Italy, 14-18 May 2001, ASP Conference ...
De Grandi, Sabrina, Molendi, Silvano
openaire +2 more sources
Cavitation nanobubbles enhancing the flotation of microfine ilmenite and associated fundamentals
Ultrasonics SonochemistryNanobubbles (NBs) have been extensively utilized in mineral flotation, acting as secondary collectors to improve flotation efficiency. However, the fundamental interaction mechanisms between NBs and flotation collector remain unclear.
Fanfan Zhang +7 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Probing Chemical Enrichment in Extremely Metal-poor Galaxies
The Astrophysical JournalThe chemical composition of galaxies offers vital insights into their formation and evolution. In particular, the relationship between helium abundance (He/H) and metallicity serves as a key diagnostic for estimating the primordial helium yield from Big ...
Keita Fukushima +6 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source