Results 41 to 50 of about 1,123,379 (326)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Assessment: A Suggested Strategy for Learning Chemical Equilibrium
Education Sciences, 2019 Chemical equilibrium is listed as one of the most complicated concepts to learn, and the origin of this phenomenon is attributed to misconceptions, teaching-related problems, and the use of inappropriate didactic approaches.
Andres Bernal-Ballen +1 more
doaj +1 more source
Analysis of Chemical Equilibrium Problem Solving Skill Through Metacognition Self-assessment [PDF]
, 2015 This research aims to describe declarative, procedural and conditional knowledge in chemical equilibrium problem solving. This research subject was 31 students of XI grade of IBC SMA Kristen Immanuel Pontianak.
Hairida, H. (Hairida) +2 more
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The chemical equilibration volume: measuring the degree of thermalization
, 2003 We address the issue of the degree of equilibrium achieved in a high energy heavy-ion collision. Specifically, we explore the consequences of incomplete strangeness chemical equilibrium.
A. Majumder +10 more
core +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Effect of simulations enhanced with conceptual change texts on university students’ understanding of chemical equilibrium [PDF]
Journal of the Serbian Chemical Society, 2018 The aim of this research was to investigate the effect of computer simulations enhanced with conceptual change texts (CS-CCT) on first year university students’ understanding of chemical equilibrium. A quasi-experimental design and one control group (CG,
Özmen Haluk, Naseriazar Akbar
doaj +1 more source
Effect of Secondary Combustion on Thrust Regulation of Gas Generator Cycle Rocket Engine
Applied Sciences, 2022 Thrust regulation is applied to maintain the performance of the liquid propellant rocket engine. The thrust level of a rocket engine can be readily controlled by adjusting the number of propellants introduced into the combustion chamber. In this study, a
Sohaib Khan +4 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source