Results 41 to 50 of about 1,129,189 (269)

Thermalization through Hagedorn states - the importance of multiparticle collisions

open access: yes, 2010
Quick chemical equilibration times of hadrons within a hadron gas are explained dynamically using Hagedorn states, which drive particles into equilibrium close to the critical temperature. Within this scheme master equations are employed for the chemical
Aoki Y   +16 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The impact of proline isomerization on antigen binding and the analytical profile of a trispecific anti-HIV antibody

open access: yesmAbs, 2020
Proline cis-trans conformational isomerization is a mechanism that affects different types of protein functions and behaviors. Using analytical characterization, structural analysis, and molecular dynamics simulations, we studied the causes of an ...
Alessandro Masiero   +23 more
doaj   +1 more source

A Systematic Study of Departures from Chemical Equilibrium in the Atmospheres of Substellar Mass Objects

open access: yes, 2007
We present a systematic study of the spectral consequences of departures from chemical equilibrium in the atmospheres of L and T dwarfs, and for even cooler dwarfs. The temperature/pressure profiles of the non-equilibrium models are fully consistent with
Burrows, Adam, Hubeny, Ivan
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

ANALYSIS OF STUDENTS MISCONCEPTION IN CHEMICAL EQUILIBRIUM MATERIAL USING THREE TIER TEST

open access: yesJTK (Jurnal Tadris Kimiya), 2020
This study aimed to analyze students misconception seen from the relationship between the results of the three tier test and interviews about chemical equilibrium material on the concept of determining the formula Kc, Kp, and the concept of Kc ...
Khairunnisa Khairunnisa   +1 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Impact parameter dependencies in Pb(160 AGeV)+Pb reactions : hydrodynamical vs. cascade calculations [PDF]

open access: yes, 2005
We investigate the impact parameter dependence of the specific entropy S/A in relativistic heavy ion collisions. Especially the anti-Lambda/anti-proton ratio is found to be a useful tool to distinguish between chemical equilibrium assumptions assumed in ...
Bleicher, Marcus   +6 more
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

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