Results 91 to 100 of about 1,642,984 (314)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

A Novel Non-Alcoholic Einkorn-Based Beverage Produced by Lactic Acid Fermentation: Microbiological, Chemical, and Sensory Assessment

Foods
Einkorn (Triticum monococcum L. ssp. monococcum) is gaining renewed interest for its high nutritional value and digestibility. Lactic acid fermentation could enhance these properties by improving micronutrient bioavailability, sensory properties, and ...
Antonietta Maoloni, Martina Cirlini, Lorenzo Del Vecchio, Raquel Torrijos, Eleonora Carini, Giorgia Rampanti, Federica Cardinali, Vesna Milanović, Cristiana Garofalo, Andrea Osimani, Lucia Aquilanti   +10 more
doaj   +1 more source

Chemical enrichment of galaxy clusters from hydrodynamical simulations

, 2007
We present cosmological hydrodynamical simulations of galaxy clusters aimed at studying the process of metal enrichment of the intra--cluster medium (ICM).
Arimoto, Balestra, Bate, Baumgartner, Bertelli, Borgani, Cen, Chiappini, Chiappini, Chieffi, Cora, Dalla Vecchia, Davé, De Grandi, De Lucia, Dolag, Domainko, F. Matteucci, Finoguenov, Finoguenov, François, Gal-Yam, Gal-Yam, Gastaldello, Gibson, Greggio, Haardt, Iwamoto, K. Dolag, Katz, Kawata, Kay, Kennicutt, Kobayashi, Kroupa, L. Tornatore, Larson, Lia, Loewenstein, Maeder, Maoz, Marigo, Matteucci, Matteucci, Matteucci, Matteucci, Matteucci, Mazzotta, Monaco, Mosconi, Murante, Mushotzky, Nagashima, Navarro, Padovani, Pipino, Portinari, Portinari, Raiteri, Rasia, Rasia, Rebusco, Recchi, Renzini, Renzini, Renzini, Roediger, Romano, Romeo, Rosati, S. Borgani, Salpeter, Samland, Sarazin, Saro, Scalo, Scannapieco, Scannapieco, Schmidt, Sijacki, Sijacki, Sommer-Larsen, Springel, Springel, Springel, Springel, Springel, Springel, Strickland, Sutherland, Tamura, Theis, Thielemann, Tormen, Tornatore, Tutukov, Valdarnini, Van Den Hoek, Vikhlinin, Vikhlinin, Voit, Woosley, Yoshikawa   +102 more
core   +2 more sources

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Galactic chemical evolution [PDF]

, 2017
We analyze the evolution of oxygen abundance radial gradients resulting from our chemical evolution models calculated with different prescriptions for the star formation rate (SFR) and for the gas infall rate, in order to assess their respective roles in
Cavichia, Oscar, Costa, Roberto Dell’Aglio Dias da, Díaz, Ángeles I., Fenner, Yeshe, Gibson, Brad K., Kawata, Daisuke, Lee, Hyun Chul, Mollá, Mercedes, Renda, Agostino   +8 more
core  

Phage-Assisted Continuous Evolution and Selection of Enzymes for Chemical Synthesis [PDF]

, 2021
Krysten A. Jones, Harrison M. Snodgrass, Ketaki D. Belsare, Bryan C. Dickinson, Jared C. Lewis   +4 more
openalex   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source