Results 91 to 100 of about 7,461,069 (375)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
How Was Nature Able to Discover Its Own Laws—Twice?
Life, 2021 The central thesis of the modern scientific revolution is that nature is objective. Yet, somehow, out of that objective reality, projective systems emerged—cognitive and purposeful.
Addy Pross
doaj +1 more source
Fluorine in the solar neighborhood : Chemical evolution models [PDF]
, 2017 Context. In light of new observational data related to fluorine abundances in solar neighborhood stars, we present chemical evolution models testing various fluorine nucleosynthesis prescriptions with the aim to best fit those new data. Aim.
E. Spitoni +4 more
semanticscholar +1 more source
, 2008 In this series of lectures we first describe the basic ingredients of galactic chemical evolution and discuss both analytical and numerical models. Then we compare model results for the Milky Way, Dwarf Irregulars, Quasars and the Intra-Cluster- Medium with abundances derived from emission lines.
openaire +2 more sources
The Chemical Evolution of the Galaxy [PDF]
Symposium - International Astronomical Union, 1985 Over the last few years, our picture of the chemical evolution of the Galaxy has changed substantially. These changes are of interest because chemical evolution provides a common point of contact for most astrophysical processes of importance to galaxy evolution.
openaire +2 more sources
FEBS Letters, EarlyView.Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa +8 more
wiley +1 more source
Frontiers in Nuclear EngineeringLong time frames are to be considered in the safety and performance assessment of deep geological disposal of intermediate and high level radioactive waste.
Guido Deissmann +2 more
doaj +1 more source
A Necessary Condition for Coexistence of Autocatalytic Replicators in a Prebiotic Environment
Life, 2013 A necessary, but not sufficient, mathematical condition for the coexistence of short replicating species is presented here. The mathematical condition is obtained for a prebiotic environment, simulated as a fed-batch reactor, which combines monomer ...
Martha A. Grover, Andres F. Hernandez
doaj +1 more source
Synthesis and Characterization of Amino Acid Decyl Esters as Early Membranes for the Origins of Life
Membranes, 2022 Understanding how membrane forming amphiphiles are synthesized and aggregate in prebiotic settings is required for understanding the origins of life on Earth 4 billion years ago.
Isabella Lago +3 more
doaj +1 more source
JINA-NuGrid Galactic Chemical Evolution Pipeline
, 2016 Galactic chemical evolution is a topic that involves nuclear physics, stellar evolution, galaxy evolution, observation, and cosmology. Continuous communication and feedback between these fields is a key component in improving our understanding of how ...
Côté, Benoit +7 more
core +1 more source