Results 101 to 110 of about 389,444 (301)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

The chemical evolution of galaxies

Metals -- heavy elements synthesized during various phases of stellar evolution or during supernova explosions -- play a fundamental role in shaping galaxy evolution. In fact, their relative abundances, spatial distribution, and scaling with galactic properties reflect the constant interplay between star-formation, nucleosynthesis, and gas flows that ...
openaire   +2 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Fluorine in the solar neighborhood : Chemical evolution models [PDF]

, 2018
Context. In light of new observational data related to fluorine abundances in solar neighborhood stars, we present chemical evolution models testing various fluorine nucleosynthesis prescriptions with the aim to best fit those new data. Aim.
ROMANO, Donatella, Romano, D., Jönsson, H.,, Ryde, N., F. Matteucci, N. Ryde, Matteucci, F.,, Jönsson, H., Spitoni, E.,, Ryde, N.,, D. Romano, E. Spitoni, H. Jönsson, Spitoni, E., Romano, D.,, Matteucci, F.   +15 more
core   +1 more source

Galactic chemical evolution [PDF]

, 2017
We analyze the evolution of oxygen abundance radial gradients resulting from our chemical evolution models calculated with different prescriptions for the star formation rate (SFR) and for the gas infall rate, in order to assess their respective roles in
Cavichia, Oscar, Mollá, Mercedes, Díaz, Ángeles I., Gibson, Brad K., Costa, Roberto Dell’Aglio Dias da   +4 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Nova contributions to the chemical evolution of the Milky Way

Context. The explosive burning that drives nova eruptions results in unique nucleosynthesis that heavily over-produces certain isotopes relative to the solar abundance.
Amanda I. Karakas, Andrew R. Casey, Benoit Côté, Zara Osborn, Alex J. Kemp, Robert G. Izzard   +5 more
core   +1 more source

From stellar to planetary composition: Galactic chemical evolution of Mg/Si mineralogical ratio [PDF]

, 2015
Aims. The main goal of this work is to study element ratios that are important for the formation of planets of different masses. Methods. We study potential correlations between the existence of planetary companions and the relative elemental abundances ...
Dorn, Caroline, Sousa, S. G., Santos, N. C., Delgado-Mena, E., V. Adibekyan, E. Delgado-Mena, S. G. Sousa, Mordasini, Christoph, A. A. Hakobyan, N. C. Santos, Hakobyan, A. A., G. Israelian, Figueira, P., Israelian, G., P. Figueira, Adibekyan, V., C. Mordasini, C. Dorn   +17 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source