Results 91 to 100 of about 389,444 (301)

Chemical evolution in planet-forming regions with growing grains

open access: yes, 2022
Context. Planets and their atmospheres are built from gas and solid material in protoplanetary disks. This solid material grows from smaller micron-sized grains to larger sizes in the disks during the process of planet formation.
Christian Eistrup   +2 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Prebiotic Chemical Evolution

open access: yes, 2013
Whereas 'natural evolution' is a well-studied biological theory, the notion of 'chemical evolution' remains ambiguous. At least two major meanings of 'chemical evolution' can be found.
Malaterre, Christophe
core  

Chemical evolution of Seyfert galaxies

open access: yes, 2008
We computed the chemical evolution of Seyfert galaxies, residing in spiral bulges, based on an updated model for the Milky Way bulge with updated calculations of the Galactic potential and of the feedback from the central supermassive black hole (BH ...
CIOTTI, LUCA   +5 more
core   +1 more source

Messy Chemistry and the Emergence of Life

open access: yesLife
Chemical complexity is not a nuisance to be minimized in origin of life research, it is an enabling condition. This second edition of the Special Issue on the Origin of Life in Chemically Complex Messy Environments gathers contributions that embrace ...
Alberto Vázquez-Salazar, Ranajay Saha
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Is Life an Unavoidable Consequence of the Formation of the Universe? Investigating the Formation of Bio-Precursors and the Signature of Earth-Like Living Forms

open access: yesFrontiers in Astronomy and Space Sciences, 2018
This contribution to the Research Topic “Imagining the Future of Astronomy and Space Sciences” focuses on astrobiology and exoplanetary research. Understanding the origin of life is the main scientific challenge to this century and an interdisciplinary ...
Ana I. Gomez de Castro
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Discharge plasma for prebiotic chemistry: Pathways to life’s building blocks

open access: yesEarth and Planetary Physics
Discharge plasmas, recognized as unique platforms for investigating the origins of chemical life, have garnered extensive interest for their potential to simulate prebiotic conditions. This paper embarks on a comprehensive overview of recent advancements
DingWei Gan   +11 more
doaj   +1 more source

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