Results 101 to 110 of about 6,446,269 (330)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Wet-Dry Cycling Delays the Gelation of Hyperbranched Polyesters: Implications to the Origin of Life

open access: yesLife, 2019
In extant biology, biopolymers perform multiple crucial functions. The biopolymers are synthesized by enzyme-controlled biosystems that would not have been available at the earliest stages of chemical evolution and consist of correctly sequenced and/or ...
Irena Mamajanov
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Chemical Evolution in Nuclear Stellar Discs [PDF]

open access: green, 2023
Jennifer K. S. Friske, Ralph Schönrich
openalex   +1 more source

Carbon and oxygen in H II regions of the Magellanic Clouds: abundance discrepancy and chemical evolution [PDF]

open access: yes, 2017
We present C and O abundances in the Magellanic Clouds derived from deep spectra of HII regions. The data have been taken with the Ultraviolet-Visual Echelle Spectrograph at the 8.2-m VLT. The sample comprises 5 HII regions in the Large Magellanic Cloud (
L. Cipriano   +15 more
semanticscholar   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

A Possible Primordial Acetyleno/Carboxydotrophic Core Metabolism

open access: yesLife, 2020
Carbon fixation, in addition to the evolution of metabolism, is a main requirement for the evolution of life. Here, we report a one-pot carbon fixation of acetylene (C2H2) and carbon monoxide (CO) by aqueous nickel sulfide (NiS) under hydrothermal (>100 °
Jessica Sobotta   +6 more
doaj   +1 more source

Molecular corridors and parameterizations of volatility in the chemical evolution of organic aerosols

open access: yes, 2016
. The formation and aging of organic aerosols (OA) proceed through multiple steps of chemical reaction and mass transport in the gas and particle phases, which is challenging for the interpretation of field measurements and laboratory experiments as well
Ying Li, U. Pöschl, M. Shiraiwa
semanticscholar   +1 more source

Mass and metallicity requirement in stellar models for galactic chemical evolution applications [PDF]

open access: yes, 2016
We used a one-zone chemical evolution model to address the question of how many metallicities and massive stars are required in grids of stellar models for galactic chemical evolution applications.
B. Cot'e   +7 more
semanticscholar   +1 more source

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