Results 121 to 130 of about 1,651,742 (317)
Deuterium Link: From Interstellar Medium and Chemical Evolution to Cosmology and Structure Formation [PDF]
Tijana Prodanović +2 more
openalex +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Chemical Evolution of Natural Product Structure. [PDF]
Grigalunas M, Brakmann S, Waldmann H.
europepmc +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Natural Radioactivity and Chemical Evolution on the Early Earth: Prebiotic Chemistry and Oxygenation. [PDF]
Ershov B.
europepmc +1 more source
The chemical evolution in the early phases of massive star formation [PDF]
Thomas Gerner +7 more
openalex +1 more source
Age-Divided Mean Stellar Populations from Full Spectrum Fitting as the Simplified Star Formation and Chemical Evolution History of a Galaxy: Methodology and Reliability [PDF]
Joon Hyeop Lee +3 more
openalex +1 more source
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source

