Results 131 to 140 of about 389,444 (301)
Natural Radioactivity and Chemical Evolution on the Early Earth: Prebiotic Chemistry and Oxygenation. [PDF]
Ershov B.
europepmc +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Chemical evolution in collapsing cores
We study the chemical evolution in the central core of contracting interstellar clouds. The chemical rate equations and the hydrodynamic equations are integrated simultaneously. The. contraction is followed from very low density (n = 10 cm(-3)) to a high-
El-Nawawy, M.S., Howe, D.A., Millar, TJ
core
Prebiotic Chemistry: The Role of Trimetaphosphate in Prebiotic Chemical Evolution. [PDF]
Gan D, Ying J, Zhao Y.
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Grand Challenges in Astrochemistry
Cristina Puzzarini, Cristina Puzzarini
doaj +1 more source
Correction to "40 Years of Duocarmycins: A Graphical Structure/Function Review of Their Chemical Evolution, from SAR to Prodrugs and ADCs". [PDF]
Felber JG, Thorn-Seshold O.
europepmc +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
The chemical evolution of solid electrolyte interface in sodium metal batteries. [PDF]
Gao L, Chen J, Chen Q, Kong X.
europepmc +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source

