Results 141 to 150 of about 367,412 (259)

Heterogeneous radiolysis of urea. Implications in astrobiology and prebiotic chemistry

Open Chemistry, 2014
Abigail E. Cruz-Hernández, Abigail E., Colin-Garcia Maria, Heredia-Barbero Alejandro, Negron-Mendoza Alicia, Ramos-Bernal Sergio   +4 more
doaj   +1 more source

Chemical Evolution of Life on Earth. [PDF]

Genes (Basel)
Lei L, Burton ZF.
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Editorial: Planetary nebulae as tools for astrophysics

Frontiers in Astronomy and Space Sciences, 2023
Miriam Peña, Karen B. Kwitter, Marcelo Miguel Miller Bertolami, Christophe Morisset, Michael Richer   +4 more
doaj   +1 more source

Chemical Evolution of Early Macromolecules: From Prebiotic Oligopeptides to Self-Organizing Biosystems via Amyloid Formation. [PDF]

Chemistry
Bencs F, Taricska N, Dürvanger Z, Horváth D, Fazekas Z, Grolmusz V, Farkas V, Perczel A.   +7 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Chemical evolution of ASO-like DNAzymes for effective and extended gene silencing in cells. [PDF]

Nucleic Acids Res
Liu Y, Zhang S, Zhang M, Liu X, Wu Y, Wu Q, Chaput JC, Wang Y.   +7 more
europepmc   +1 more source

Tracking the Chemical Evolution of Iodine Species Using Recurrent Neural Networks. [PDF]

ACS Omega, 2020
Bilbrey JA, Marrero CO, Sassi M, Ritzmann AM, Henson NJ, Schram M.   +5 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Chemical Evolution of Biomass Burning Aerosols across Wildfire Plumes in the Western U.S.: From Near-Source to Regional Scales. [PDF]

ACS EST Air
Farley R, Zhou S, Collier S, Jiang W, Onasch TB, Shilling JE, Kleinman L, Sedlacek Iii AJ, Zhang Q.   +8 more
europepmc   +1 more source