Results 141 to 150 of about 7,461,069 (375)

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

Understanding the various evolutionary stages of the low-mass star-formation process by SO and SO2

Frontiers in Astronomy and Space Sciences
SO and SO2 are two potential candidates to trace the different evolutionary phases of the low-mass star-formation process. Here, we report observations of SO and SO2 along with their isotopologues, 34SO and 34SO2, respectively, in four distinct phases of
Rana Ghosh, Rana Ghosh, Ankan Das, Ankan Das, Prasanta Gorai, Prasanta Gorai, Suman Kumar Mondal, Kenji Furuya, Kenji Furuya, Kei E. I. Tanaka, Takashi Shimonishi   +10 more
doaj   +1 more source

The building up of the disk galaxy M33 and the evolution of the metallicity gradient

, 2007
The evolution of radial gradients of metallicity in disk galaxies and its relation with the disk formation are not well understood. Theoretical models of galactic chemical evolution make contrasting predictions about the time evolution of metallicity ...
Aller, Arnett, Aubert, Beaulieu, Block, Block, Brooks, Bullock, Chabrier, Chang, Chiappini, Chiappini, Chiappini, Chieffi, Ciardullo, Ciardullo, Corbelli, Corbelli, Crockett, D. Galli, Davidge, de Boer, Devereux, Diaz, E. Corbelli, Elmegreen, Engargiola, Ferrini, Ferrini, Ferrini, Ferrini, Freedman, Freeman, Friel, Gallagher, Galletti, Garnett, Gavilán, Goetz, Henry, Henry, Henry, Herrero, Herwig, Heyer, Hippelein, Hirschi, Holmberg, Hoopes, Hou, Israel, Kennicutt, Kennicutt, Kennicutt, Keres, Kim, Koeppen, Kroupa, Kroupa, Kwitter, L. Magrini, Maciel, Maciel, Maciel, Maciel, Magrini, Magrini, Magrini, Marigo, McCarthy, McConnachie, Mollà, Mollà, Mollà, Monteverde, Monteverde, Naab, Newton, Portinari, Portinari, Regan, Richer, Romano, Rowe, Salpeter, Sandage, Scalo, Scalo, Smith, Stanghellini, Stephens, Talbot, Thielemann, Tiede, Tinsley, Tosi, Urbaneja, Venn, Vílchez, Wakker, Westmeier, Willner, Woosley, Wyse, Young   +104 more
core   +1 more source

Planet signatures and effect of the chemical evolution of the Galactic thin-disk stars [PDF]

, 2015
Context: Studies based on high-precision abundance determinations revealed that chemical patterns of solar twins are characterised by the correlation between the differential abundances relative to the Sun and the condensation temperatures (Tc) of the ...
L. Spina, J. Mel'endez, I. Ram'irez
semanticscholar   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

A Novel Non-Alcoholic Einkorn-Based Beverage Produced by Lactic Acid Fermentation: Microbiological, Chemical, and Sensory Assessment

Foods
Einkorn (Triticum monococcum L. ssp. monococcum) is gaining renewed interest for its high nutritional value and digestibility. Lactic acid fermentation could enhance these properties by improving micronutrient bioavailability, sensory properties, and ...
Antonietta Maoloni, Martina Cirlini, Lorenzo Del Vecchio, Raquel Torrijos, Eleonora Carini, Giorgia Rampanti, Federica Cardinali, Vesna Milanović, Cristiana Garofalo, Andrea Osimani, Lucia Aquilanti   +10 more
doaj   +1 more source

Galactic chemical evolution: stellar yields and the initial mass function [PDF]

, 2015
We present a set of 144 galactic chemical evolution models applied to a Milky Way analogue, computed using four sets of low+intermediate star nucleosynthetic yields, six massive sta r yield compilations, and six functional forms for the initia l mass ...
M. Moll'a, O. Cavichia, M. Gavil'an, B. Gibson   +3 more
semanticscholar   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

FEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel, A. F. Volker Wagner, R. Gary Sawers   +2 more
wiley   +1 more source

Is Life an Unavoidable Consequence of the Formation of the Universe? Investigating the Formation of Bio-Precursors and the Signature of Earth-Like Living Forms

Frontiers in Astronomy and Space Sciences, 2018
This contribution to the Research Topic “Imagining the Future of Astronomy and Space Sciences” focuses on astrobiology and exoplanetary research. Understanding the origin of life is the main scientific challenge to this century and an interdisciplinary ...
Ana I. Gomez de Castro
doaj   +1 more source