Results 191 to 200 of about 1,642,984 (314)

Metal-ion mediated photolytic regulation of diphenylalanine stability: Implications for prebiotic chemical evolution. [PDF]

iScience
Tang W, Shi X, Shen J, Mao H, Wei E, Huang B, Ying J, Cai H, Zhao Y.   +8 more
europepmc   +1 more source

The Role of the IGIMF in the chemical evolution of the solar neighbourhood [PDF]

, 2011
F. Calura, S. Recchi, F. Matteuccí, Pavel Kroupa   +3 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Chemical Evolution of Life on Earth. [PDF]

Genes (Basel)
Lei L, Burton ZF.
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Chemical Evolution of Early Macromolecules: From Prebiotic Oligopeptides to Self-Organizing Biosystems via Amyloid Formation. [PDF]

Chemistry
Bencs F, Taricska N, Dürvanger Z, Horváth D, Fazekas Z, Grolmusz V, Farkas V, Perczel A.   +7 more
europepmc   +1 more source

Structure evolution upon chemical and physical pressure in (Sr1−xBax)2FeSbO6

, 2016
Taneli Tiittanen, Maarit Karppinen
openalex   +2 more sources

Texture Development, Microstructure Evolution, and Crystallization of Chemically Derived PZT Thin Films [PDF]

, 1998
San‐Yuan Chen, I‐Wei Chen
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Chemical evolution of ASO-like DNAzymes for effective and extended gene silencing in cells. [PDF]

Nucleic Acids Res
Liu Y, Zhang S, Zhang M, Liu X, Wu Y, Wu Q, Chaput JC, Wang Y.   +7 more
europepmc   +1 more source