Results 191 to 200 of about 1,651,742 (317)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Chemical Evolution of Life on Earth. [PDF]

Genes (Basel)
Lei L, Burton ZF.
europepmc   +1 more source

APPLICATION OF POLYCARBONATE AND POLYMER COATINGS IN THE CONSTRUCTION INDUSTRY IN EUROPE AND ASIA: PHYSICO-CHEMICAL BASIS, TECHNOLOGICAL ADVANTAGES AND GLOBAL MARKET EVOLUTION

G'aniyev, Alijon, Abdulhakimov, Muhammadyusuf   +1 more
openalex   +1 more source

On an alternative approach for simulating chemically induced crack pattern evolutions in a single crystal

, 2020
Jožef Predan, Marko Kegl, Rainer Abart, F.D. Fischer, F.G. Rammerstorfer   +4 more
openalex   +1 more source

Comet impacts and chemical evolution on the bombarded Earth [PDF]

, 1991
V. R. Oberbeck, H. R. Aggarwal
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Chemical Evolution of Early Macromolecules: From Prebiotic Oligopeptides to Self-Organizing Biosystems via Amyloid Formation. [PDF]

Chemistry
Bencs F, Taricska N, Dürvanger Z, Horváth D, Fazekas Z, Grolmusz V, Farkas V, Perczel A.   +7 more
europepmc   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Editorial: Planetary nebulae as tools for astrophysics

Frontiers in Astronomy and Space Sciences, 2023
Miriam Peña, Karen B. Kwitter, Marcelo Miguel Miller Bertolami, Christophe Morisset, Michael Richer   +4 more
doaj   +1 more source

Chemical evolution of ASO-like DNAzymes for effective and extended gene silencing in cells. [PDF]

Nucleic Acids Res
Liu Y, Zhang S, Zhang M, Liu X, Wu Y, Wu Q, Chaput JC, Wang Y.   +7 more
europepmc   +1 more source