Inhomogeneous chemical evolution of the Galactic disk
G. Malinie+3 more
openalex +1 more source
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
Chemical evolution characteristics and influencing factors of groundwater in the saline and fresh water funnel area in Hengshui City, North China. [PDF]
Yu Y, Yan B, Tuo Y, Zhan X, Xie X.
europepmc +1 more source
Thermal and Chemical Evolution of X-Ray Clusters of Galaxies [PDF]
Junji Fukumoto, Satoru Ikeuchi
openalex +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
Alkaline saline lakes: A chemical evolution experiment evaluating the stability of formaldehyde in an aqueous saline environment. [PDF]
Fuentes-Carreón CA+3 more
europepmc +1 more source
Structural and chemical evolution of Au-silica core-shell nanoparticles during 20 keV helium ion irradiation: a comparison between experiment and simulation. [PDF]
Mousley M+5 more
europepmc +1 more source
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Chemical Evolution and Biological Evaluation of Natural Products for Efficient Therapy of Acute Lung Injury. [PDF]
Fan C+9 more
europepmc +1 more source