Results 241 to 250 of about 7,461,069 (375)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Chemical evolution characteristics and influencing factors of groundwater in the saline and fresh water funnel area in Hengshui City, North China. [PDF]

Sci Rep
Yu Y, Yan B, Tuo Y, Zhan X, Xie X.
europepmc   +1 more source

Structural and chemical evolution of Au-silica core-shell nanoparticles during 20 keV helium ion irradiation: a comparison between experiment and simulation. [PDF]

Sci Rep, 2020
Mousley M, Möller W, Philipp P, Hlawacek G, Wirtz T, Eswara S.   +5 more
europepmc   +1 more source

Chemical Evolution of Galaxies and Quasar Metallicities

, 1993
F. Matteuccí, P. Padovani
openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Alkaline saline lakes: A chemical evolution experiment evaluating the stability of formaldehyde in an aqueous saline environment. [PDF]

Heliyon
Fuentes-Carreón CA, Meléndez-López AL, Cruz-Castañeda JA, Negrón-Mendoza A.   +3 more
europepmc   +1 more source

Chemical evolution of irregular galaxies and the primordial He-4 abundance

, 1993
Grant J. Mathews, R. N. Boyd, George M. Fuller   +2 more
openalex   +1 more source

Thresholds on star formation and the chemical evolution of galactic discs: cosmochronology and the age of the Galaxy [PDF]

, 1996
Khalil Chamcham, M. Hendry
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Chemical Evolution and Biological Evaluation of Natural Products for Efficient Therapy of Acute Lung Injury. [PDF]

Adv Sci (Weinh)
Fan C, Zhang Z, Lai Z, Yang Y, Li J, Liu L, Chen S, Hu X, Zhao H, Cui S.   +9 more
europepmc   +1 more source