Results 61 to 70 of about 6,446,269 (330)

Prebiotic Chemistry: Geochemical Context and Reaction Screening

Life, 2013
The origin of life on Earth is widely believed to have required the reactions of organic compounds and their self- and/or environmental organization. What those compounds were remains open to debate, as do the environment in and process or processes by ...
Henderson James Cleaves
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

EURAD State-of-the-Art Report: Assessment of the chemical evolution at the disposal cell scale – part II – gaining insights into the geochemical evolution

Frontiers in Nuclear Engineering
Long time frames are to be considered in the safety and performance assessment of deep geological disposal of intermediate and high level radioactive waste.
Guido Deissmann, Erika Neeft, Diederik Jacques   +2 more
doaj   +1 more source

A Physicochemical Consideration of Prebiotic Microenvironments for Self-Assembly and Prebiotic Chemistry

Life, 2022
The origin of life on Earth required myriads of chemical and physical processes. These include the formation of the planet and its geological structures, the formation of the first primitive chemicals, reaction, and assembly of these primitive chemicals ...
Arpita Saha, Ruiqin Yi, Albert C. Fahrenbach, Anna Wang, Tony Z. Jia   +4 more
doaj   +1 more source

Inflow, Outflow, Yields, and Stellar Population Mixing in Chemical Evolution Models [PDF]

, 2016
Chemical evolution models are powerful tools for interpreting stellar abundance surveys and understanding galaxy evolution. However, their predictions depend heavily on the treatment of inflow, outflow, star formation efficiency (SFE), the stellar ...
B. Andrews, D. Weinberg, R. Schönrich, Jennifer A. Johnson   +3 more
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Molecular Asymmetry in Prebiotic Chemistry: An Account from Meteorites

Life, 2016
Carbonaceous Chondrite (CC) meteorites are fragments of asteroids, solar planetesimals that never became large enough to separate matter by their density, like terrestrial planets.
Sandra Pizzarello
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Pyrophosphate and Irreversibility in Evolution, or why PPi Is Not an Energy Currency and why Nature Chose Triphosphates

Frontiers in Microbiology, 2021
The possible evolutionary significance of pyrophosphate (PPi) has been discussed since the early 1960s. Lipmann suggested that PPi could have been an ancient currency or a possible environmental source of metabolic energy at origins, while Kornberg ...
Jessica L. E. Wimmer, Karl Kleinermanns, William F. Martin   +2 more
doaj   +1 more source

GALACTIC CHEMICAL EVOLUTION: THE IMPACT OF THE 13C-POCKET STRUCTURE ON THE s-PROCESS DISTRIBUTION [PDF]

, 2017
The solar s-process abundances have been analyzed in the framework of a Galactic Chemical Evolution (GCE) model. The aim of this work is to implement the study by Bisterzo et al., who investigated the effect of one of the major uncertainties of ...
S. Bisterzo, C. Travaglio, M. Wiescher, F. Käppeler, R. Gallino   +4 more
semanticscholar   +1 more source