Results 71 to 80 of about 7,461,069 (375)
The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
THE PROTOBIOLOGICAL THEORY OF CEILINGS AND FLOORS, OR CHEMICAL EVOLUTION AS A PLANETARY PROCESS [PDF]
Filozofia i NaukaThe article presents a modern protobiological theory based on the classical archetype. It connects the issues of origins of life with the theory of the hierarchy of matter and recognizes that error correction occurs within hierarchical and dynamic living
Alicja Kubica
doaj +1 more source
Galactic chemical evolution [PDF]
, 2017 We analyze the evolution of oxygen abundance radial gradients resulting from our chemical evolution models calculated with different prescriptions for the star formation rate (SFR) and for the gas infall rate, in order to assess their respective roles in
Cavichia, Oscar +8 more
core
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
Frontiers in Microbiology, 2021 The possible evolutionary significance of pyrophosphate (PPi) has been discussed since the early 1960s. Lipmann suggested that PPi could have been an ancient currency or a possible environmental source of metabolic energy at origins, while Kornberg ...
Jessica L. E. Wimmer +2 more
doaj +1 more source
Equilibrium and Sudden Events in Chemical Evolution [PDF]
, 2016 We present new analytic solutions for one-zone (fully mixed) chemical evolution models that incorporate a realistic delay time distribution for Type Ia supernovae (SNe Ia) and can therefore track the separate evolution of α-elements produced by core ...
D. Weinberg +2 more
semanticscholar +1 more source
Chemical Evolution of a Bacterium’s Genome [PDF]
Angewandte Chemie International Edition, 2011 We set out to develop a generic technology for evolving the chemical constitution of microbial populations by using the simplest possible algorithm. Extant living cells polymerize a restricted set of nucleic acid precursors, namely, four nucleoside triphosphates (UTP, CTP, ATP, GTP) and four deoxynucleoside triphosphates (dTTP, dCTP, dATP, dGTP ...
Madeleine Bouzon +9 more
openaire +4 more sources
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Chemical Evolution Tomorrow [PDF]
, 2002 The solar system is just one sample, though of course the most thoroughly studied sample, of cosmic chemistry. Some perspective on it can be gained from an overview of the chemical evolution of the Galaxy and Universe, how our knowledge of this evolution has developed, and what problems remain to be solved.
Virginia Trimble, Virginia Trimble
openaire +3 more sources
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source